A-Trifluoroacetyl-G-butyrolactone

Base Information

• Chemical Name: A-Trifluoroacetyl-G-butyrolactone
• CAS No.: 69243-04-5
• Molecular Formula: C₆H₅F₃O₃
• Molecular Weight: 182.099
• Hs Code.: 2932209090
• DSSTox Substance ID: DTXSID20500956
• Nikkaji Number: J2.718.213E
• Mol file: 69243-04-5.mol

Synonyms:A-TRIFLUOROACETYL-G-BUTYROLACTONE;69243-04-5;3-(2,2,2-Trifluoro-acetyl)-dihydro-furan-2-one;3-(2,2,2-TRIFLUOROACETYL)OXOLAN-2-ONE;3-(2,2,2-trifluoroacetyl)dihydrofuran-2(3H)-one;3-(trifluoroacetyl)oxolan-2-one;SCHEMBL9238583;DTXSID20500956;UGCNKKXWKVWELR-UHFFFAOYSA-N;MFCD00525555;AKOS006273403;CS-0454943;3-(2,2,2-Trifluoroacetyl)tetrahydrofuran-2-one

Chemical Property of A-Trifluoroacetyl-G-butyrolactone

Chemical Property:

• PSA: 43.37000
• LogP: 0.68090
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 182.01907850
• Heavy Atom Count: 12
• Complexity: 221

Purity/Quality:

98%min ^*data from raw suppliers

alpha-Trifluoroacetyl-gamma-butyrolactone 90% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC(=O)C1C(=O)C(F)(F)F

Technology Process of A-Trifluoroacetyl-G-butyrolactone

There total 1 articles about A-Trifluoroacetyl-G-butyrolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ α-(2,2,2-trifluoroacetyl)-γ-butyrolactone (69243-04-5)

Guidance literature:

γ-Butyrolacton, Trifluoressigester, NaH;

DOI:10.1021/jm00189a017

Reference yield:

α-(2,2,2-trifluoroacetyl)-γ-butyrolactone (69243-04-5) + benzamidin (618-39-3) → 5,6-dihydro-4-trifluoromethylfurano<2,3-d>pyrimidine + 5-(2-hydroxyethyl)-2-phenyl-6-trifluoromethylpyrimidin-4-one

Guidance literature:

With KPTS; In toluene; Heating;