Levodione

Base Information

Chemical Name:Levodione
CAS No.:60046-49-3
Molecular Formula:C9H14O2
Molecular Weight:154.209
Hs Code.:
DSSTox Substance ID:DTXSID601335381
Nikkaji Number:J946.010A
Wikidata:Q27159134
Mol file:60046-49-3.mol

Synonyms:dihydrooxoisophorone;DOIP cpd;levodione

Suppliers and Price of Levodione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(6R)-Levodione
5g
$ 780.00

TRC
(6R)-Levodione
2.5g
$ 400.00

TRC
(6R)-Levodione
1g
$ 175.00

Total 1 raw suppliers

Chemical Property of Levodione

Chemical Property:

PSA：34.14000
LogP:1.58070
Solubility.:Dichloromethane; Methanol; Ethyl Acetate;
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:154.099379685
Heavy Atom Count:11
Complexity:204

Purity/Quality:: (6R)-Levodione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=O)CC(C1=O)(C)C
Isomeric SMILES:C[C@@H]1CC(=O)CC(C1=O)(C)C
Uses (6R)-Levodione is an intermediate used in the synthesis of Xanthoxin (X742550), which is a growth inhibitor in plants.

Technology Process of Levodione

There total 9 articles about Levodione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1125-21-9
2,6,6-trimethyl-2-cyclohexene-1,4-dione

: 55058-51-0
(4S)-hydroxy-(6R)-2,2,6-trimethylcyclohexanone

: 60046-49-3
(6R)-levodione

Guidance literature:: With D-glucose; Saccharomyces cerevisiae (baker's yeast, Fermix(R)); oxygen; In ethanol; for 48h; Further Variations:; conc. of educt and reagents; Product distribution; Kinetics;
DOI:10.1002/adsc.200505024

Reference yield: 81.1%

: 1125-21-9
2,6,6-trimethyl-2-cyclohexene-1,4-dione

: 60046-49-3
(6R)-levodione

: 60686-83-1
(6S)-2,2,6-trimethylcyclohexane-1,4-dione

Guidance literature:: With recombinant old yellow enzyme from Bacillus subtilis; water; chromium; Flavin mononucleotide; In aq. buffer; at 21 ℃; for 4h; pH=6.5; stereoselective reaction; Glovebox; Darkness; Inert atmosphere; Enzymatic reaction;
DOI:10.1002/cbic.201900685

Reference yield: 80.0%

: 1125-21-9
2,6,6-trimethyl-2-cyclohexene-1,4-dione

: 60046-49-3
(6R)-levodione

Guidance literature:: With D-glucose; YqjM-RBS-GDH; NADPH; In aq. buffer; at 30 ℃; for 12h; pH=7.5; enantioselective reaction; Ionic liquid; Green chemistry; Enzymatic reaction;
DOI:10.1039/d1gc00372k