1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)

Base Information

Chemical Name:1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)
CAS No.:679436-55-6
Molecular Formula:C₇H₈N₂O₅
Molecular Weight:200.151
Hs Code.:
Mol file:679436-55-6.mol

Synonyms:1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)

Suppliers and Price of 1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(carboxymethoxy)-1-methylpyrazole-3-carboxylicAcid
10mg
$ 45.00

Crysdot
5-(Carboxymethoxy)-1-methyl-1H-pyrazole-3-carboxylicacid 95+%
1g
$ 817.00

Crysdot
5-(Carboxymethoxy)-1-methyl-1H-pyrazole-3-carboxylicacid 95+%
5g
$ 2456.00

AK Scientific
5-(carboxymethoxy)-1-methylpyrazole-3-carboxylicacid
1g
$ 887.60

Total 3 raw suppliers

Chemical Property of 1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)

Chemical Property:

Boiling Point:482.5±30.0 °C(Predicted)
PKA:3.07±0.10(Predicted)
PSA：101.65000
Density:1.57±0.1 g/cm3(Predicted)
LogP:-0.41830

Purity/Quality:

99% ^*data from raw suppliers

5-(carboxymethoxy)-1-methylpyrazole-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI)

There total 2 articles about 1H-Pyrazole-3-carboxylicacid,5-(carboxymethoxy)-1-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 679436-56-7
5-[(ethoxycarbonyl)methoxy]-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester

: 679436-55-6
5-(carboxymethoxy)-1-methyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; at 100 ℃; for 1h;
DOI:10.1021/jm0309654

Reference yield:

: 51985-95-6
methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate

: 679436-55-6
5-(carboxymethoxy)-1-methyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone / 2 h / Heating

2: aq. NaOH / methanol / 1 h / 100 °C

With sodium hydroxide; potassium carbonate; In methanol; acetone;
DOI:10.1021/jm0309654

Reference yield:

: 679436-55-6
5-(carboxymethoxy)-1-methyl-1H-pyrazole-3-carboxylic acid

: 2-[5-(1,3-diisobutyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-2-methyl-2H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / toluene-4-sulfonic acid / 20 °C

2: EDAC / methanol / 5 h / 20 °C

3: aq. NaOH / 0.5 h / 70 °C

4: 47 percent / EDAC; HOBt / dimethylformamide / 5 h / 20 °C

With sodium hydroxide; benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0309654