10.1021/ic802286u
The study focuses on the synthesis, structural characterization, and reactivity of palladium(II) aminodiphosphine PNP pincer complexes, specifically the dialkylamides [PdR(PNP)] (where R is Cl, Me, Ph; PNP is (NCH2CH2PiPr2)2). These complexes were prepared and characterized to understand their role in C-N coupling reactions, which are significant in cross-coupling reactions like the Hartwig-Buchwald process. The chemicals used include palladium(II) salts, KOBu, AgPF6, TlPF6, MeOTf, PMe3, CNtBu, and various solvents like benzene, THF, and pentane. These reagents and solvents serve various purposes such as deprotonation, chloride abstraction, oxidation, and methylation reactions, as well as solvents for reactions and purification steps. The study aims to provide insights into the molecular structures, basicity (pKa values), and reactivity patterns of these complexes, which are crucial for understanding catalytic mechanisms in C-N bond formation. The results indicate that the palladium PNP dialkylamido complexes are stable, feature pyramidal nitrogen atoms, and exhibit reactivity towards electrophiles and oxidizing agents, with the reactivity being influenced by the nature of the ligands and the palladium-nitrogen bonding.
