2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE

Base Information

• Chemical Name: 2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE
• CAS No.: 681249-78-5
• Molecular Formula: C₈H₁₂N₄
• Molecular Weight: 164.21
• Hs Code.: 2933990090
• Mol file: 681249-78-5.mol

Synonyms:2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE

Chemical Property of 2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE

Chemical Property:

• Boiling Point: 382.2±52.0 °C(Predicted)
• PKA: 6.83±0.20(Predicted)
• PSA: 42.74000
• Density: 1.63±0.1 g/cm3(Predicted)
• LogP: 0.58750

Purity/Quality:

99%min ^*data from raw suppliers

2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]-TRIAZOLO-[1,5-A]-PYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE

There total 1 articles about 2-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H8N4 (681249-76-3) → C8H12N4 (681249-78-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2007.07.100

Reference yield:

C8H12N4 (681249-78-5) + (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid (486460-00-8,922178-94-7) → C23H28F3N5O3 (681249-80-9)

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1016/j.bmcl.2007.07.100

upstream raw materials:

C₈H₈N₄

Downstream raw materials:

C₂₃H₂₈F₃N₅O₃

Refernces