4-(6-Morpholino-3-nitro-2-pyridyl)morpholine

Base Information

Chemical Name:4-(6-Morpholino-3-nitro-2-pyridyl)morpholine
CAS No.:61100-30-9
Molecular Formula:C13H18N4O4
Molecular Weight:294.30642
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40371266
Wikidata:Q82158549
Mol file:61100-30-9.mol

Synonyms:61100-30-9;4-(6-morpholino-3-nitro-2-pyridyl)morpholine;4-(6-morpholin-4-yl-5-nitropyridin-2-yl)morpholine;2,6-Dimorpholino-3-nitropyridine;2,6-Di(morpholin-4-yl)-3-nitropyridine;Maybridge1_008231;HMS564O03;Oprea1_249359;DTXSID40371266;4,4'-(3-Nitropyridine-2,6-diyl)dimorpholine;4,4'-(3-Nitropyridine-2,6-diyl)bis(morpholine);4-[6-(morpholin-4-yl)-5-nitropyridin-2-yl] morpholine

Suppliers and Price of 4-(6-Morpholino-3-nitro-2-pyridyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,6-DI(MORPHOLIN-4-YL)-3-NITROPYRIDINE 95.00%
250MG
$ 854.01

American Custom Chemicals Corporation
2,6-DI(MORPHOLIN-4-YL)-3-NITROPYRIDINE 95.00%
100MG
$ 730.31

Total 3 raw suppliers

Chemical Property of 4-(6-Morpholino-3-nitro-2-pyridyl)morpholine

Chemical Property:

PSA：83.65000
LogP:1.31620
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:294.13280507
Heavy Atom Count:21
Complexity:353

Purity/Quality:

99% ^*data from raw suppliers

2,6-DI(MORPHOLIN-4-YL)-3-NITROPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NC(=C(C=C2)[N+](=O)[O-])N3CCOCC3

Technology Process of 4-(6-Morpholino-3-nitro-2-pyridyl)morpholine

There total 2 articles about 4-(6-Morpholino-3-nitro-2-pyridyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 110-91-8,99108-56-2
morpholine

: 16013-85-7,136901-10-5
2,6-dicholoro-3-nitropyridine

: 61100-30-9
4,4’-(3-nitropyridine-2,6-diyl)dimorpholine

: 1094323-33-7
4-(6-chloro-3-nitropyridin-2-yl)morpholine

Guidance literature:: With triethylamine; In acetonitrile; at 0 - 20 ℃; for 3.5h;
DOI:10.1039/c9ob00511k

Reference yield:

: 61100-30-9
4,4’-(3-nitropyridine-2,6-diyl)dimorpholine

Guidance literature:: Aus 2,6-Dichlor-3-nitro-pyridin u. Morpholin;

Reference yield: 82.0%

: 61100-30-9
4,4’-(3-nitropyridine-2,6-diyl)dimorpholine

: 157033-24-4
3,5-difluorophenylacetyl chloride

: 2-(3,5-difluorophenyl)-N-(2,6-dimorpholinopyridin-3-yl)acetamide

Guidance literature:: 4,4’-(3-nitropyridine-2,6-diyl)dimorpholine; With palladium 10% on activated carbon; hydrogen; In isopropyl alcohol;

3,5-difluorophenylacetyl chloride; With triethylamine; for 2h;
DOI:10.1039/c9ob00511k