2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol

Base Information

Chemical Name:2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol
CAS No.:682802-83-1
Molecular Formula:C₁₇H₁₇NO₂
Molecular Weight:267.327
Hs Code.:
DSSTox Substance ID:DTXSID00479373
Mol file:682802-83-1.mol

Synonyms:682802-83-1;6-Benzyloxytryptophol;2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol;2-(6-Benzyloxy-1H-indol-3-yl)-ethanol;2-[6-(Benzyloxy)-1H-indol-3-yl]ethan-1-ol;2-(6-phenylmethoxy-1H-indol-3-yl)ethanol;DTXSID00479373;MFCD02683921;B-2255

Suppliers and Price of 2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(6-BENZYLOXY-1H-INDOL-3-YL)-ETHANOL 95.00%
5MG
$ 502.32

Total 2 raw suppliers

Chemical Property of 2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol

Chemical Property:

PSA：45.25000
LogP:3.28170
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:267.125928785
Heavy Atom Count:20
Complexity:291

Purity/Quality:

98%Min ^*data from raw suppliers

2-(6-BENZYLOXY-1H-INDOL-3-YL)-ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=CN3)CCO

Technology Process of 2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol

There total 3 articles about 2-(6-(Benzyloxy)-1H-indol-3-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 859871-38-8
6-benzyloxy-2-trimethylsilanyl-3-(2-trimethylsilanyloxy-ethyl)-1H-indole

: 682802-83-1
2-(6-benzyloxy-1H-indol-3-yl)-ethanol

Guidance literature:: With acetyl chloride; In methanol; at 0 ℃; for 0.25h;
DOI:10.1055/s-2005-868485

Reference yield:

: 859871-33-3
5-(benzyloxy)-2-iodoaniline

: 682802-83-1
2-(6-benzyloxy-1H-indol-3-yl)-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: LiCl; PPh₃; K₂CO₃ / Pd(OAc)2 / dimethylformamide / 2 h / 80 °C

2: AcCl / methanol / 0.25 h / 0 °C

With potassium carbonate; acetyl chloride; triphenylphosphine; lithium chloride; palladium diacetate; In methanol; N,N-dimethyl-formamide;
DOI:10.1055/s-2005-868485

Reference yield:

: 183007-32-1
4-benzyloxy-1-iodo-2-nitrobenzene

: 682802-83-1
2-(6-benzyloxy-1H-indol-3-yl)-ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / H₂NNH₂; FeCl₃*H₂O; activated charcoal / methanol / 38 h / Heating

2: LiCl; PPh₃; K₂CO₃ / Pd(OAc)2 / dimethylformamide / 2 h / 80 °C

3: AcCl / methanol / 0.25 h / 0 °C

With iron(III) chloride; potassium carbonate; pyrographite; acetyl chloride; triphenylphosphine; lithium chloride; hydrazine; palladium diacetate; In methanol; N,N-dimethyl-formamide;
DOI:10.1055/s-2005-868485