N1,N12-Diacetylspermine

Base Information

• Chemical Name: N1,N12-Diacetylspermine
• CAS No.: 61345-83-3
• Molecular Formula: C14H30N4O2
• Molecular Weight: 286.41
• DSSTox Substance ID: DTXSID10276330
• Nikkaji Number: J393.742I
• Wikidata: Q3869332
• Metabolomics Workbench ID: 38057
• Mol file: 61345-83-3.mol

Synonyms:N1,N12-Diacetylspermine;61345-83-3;N(1),N(12)-diacetylspermine;N,N'-[1,4-Butanediylbis(imino-3,1-propanediyl)]bis-acetamide;DASpm;N,N'-[butane-1,4-diylbis(iminopropane-3,1-diyl)]diacetamide;C03413;SCHEMBL19961838;CHEBI:28101;DTXSID10276330;Acetamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis-;Q3869332;N-[3-({4-[(3-acetamidopropyl)amino]butyl}amino)propyl]acetamide;(Z)-N-(3-{[4-({3-[(Z)-(1-hydroxyethylidene)amino]propyl}amino)butyl]amino}propyl)ethanimidic acid

Chemical Property of N1,N12-Diacetylspermine

Chemical Property:

• Boiling Point: 544oC at 760 mmHg
• Flash Point: 194.3oC
• PSA: 89.24000
• Density: 0.99g/cm3
• LogP: 2.46060
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 13
• Exact Mass: 286.23687621
• Heavy Atom Count: 20
• Complexity: 234

Purity/Quality:

N1,N12-Diacetylspermine hydrochloride analyticalstandard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NCCCNCCCCNCCCNC(=O)C
• Uses: N1,N12-Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.[Cayman Chemical]