Tert-butyl (5-formyl-2-naphthyl)carbamate

Base Information

Chemical Name:Tert-butyl (5-formyl-2-naphthyl)carbamate
CAS No.:685902-48-1
Molecular Formula:C₁₆H₁₇NO₃
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID00700558
Wikidata:Q82631961
Mol file:685902-48-1.mol

Synonyms:685902-48-1;TERT-BUTYL (5-FORMYL-2-NAPHTHYL)CARBAMATE;DTXSID00700558;BENZYLALPHA-D-GLUCOPYRANOSIDE;tert-Butyl (5-formylnaphthalen-2-yl)carbamate

Suppliers and Price of Tert-butyl (5-formyl-2-naphthyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-(5-FORMYL-2-NAPHTHYL)CARBAMATE 95.00%
5MG
$ 500.20

AccelPharmtech
tert-butyl5-formylnaphthalen-2-ylcarbamate 97.00%
25G
$ 8510.00

AccelPharmtech
tert-butyl5-formylnaphthalen-2-ylcarbamate 97.00%
5G
$ 4530.00

AccelPharmtech
tert-butyl5-formylnaphthalen-2-ylcarbamate 97.00%
1G
$ 2640.00

Total 3 raw suppliers

Chemical Property of Tert-butyl (5-formyl-2-naphthyl)carbamate

Chemical Property:

PSA：55.40000
LogP:4.07230
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:361

Purity/Quality:

97% ^*data from raw suppliers

TERT-BUTYL-(5-FORMYL-2-NAPHTHYL)CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC2=C(C=C1)C(=CC=C2)C=O

Technology Process of Tert-butyl (5-formyl-2-naphthyl)carbamate

There total 5 articles about Tert-butyl (5-formyl-2-naphthyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 685902-47-0
(5-cyanonaphthalen-2-yl)carbamic acid tert-butyl ester

: 685902-48-1
(5-formylnaphthalen-2-yl)carbamic acid tert-butyl ester

Guidance literature:: (5-cyanonaphthalen-2-yl)carbamic acid tert-butyl ester; With pyridine; In acetic acid; for 0.5h;

With pyridine; nickel; In acetic acid; at 46 ℃; for 1.5h;
DOI:10.1021/jm030540h

Reference yield:

: 67878-76-6
5-bromo-2-naphthalenecarboxylic acid methyl ester

: 685902-48-1
(5-formylnaphthalen-2-yl)carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine / dimethylformamide / 6 h / 160 °C

2.1: aq. NaOH / methanol / 20 °C

3.1: 4.2 g / Et₃N; phosphorazidic acid diphenyl ester / 72 h

4.1: pyridine / acetic acid / 0.5 h

4.2: 2.71 g / Raney Ni; pyridine / acetic acid / 1.5 h / 46 °C

With pyridine; sodium hydroxide; diphenyl phosphoryl azide; triethylamine; In methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm030540h

Reference yield:

: 1013-83-8
5-bromonaphthalene-2-carboxylic acid

: 685902-48-1
(5-formylnaphthalen-2-yl)carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: 3.82 g / HCl(g) / 5 h / Heating

2.1: pyridine / dimethylformamide / 6 h / 160 °C

3.1: aq. NaOH / methanol / 20 °C

4.1: 4.2 g / Et₃N; phosphorazidic acid diphenyl ester / 72 h

5.1: pyridine / acetic acid / 0.5 h

5.2: 2.71 g / Raney Ni; pyridine / acetic acid / 1.5 h / 46 °C

With pyridine; hydrogenchloride; sodium hydroxide; diphenyl phosphoryl azide; triethylamine; In methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm030540h