Izonsteride

Base Information

Chemical Name:Izonsteride
CAS No.:176975-26-1
Molecular Formula:C₂₄H₂₆N₂OS₂
Molecular Weight:422.615
Hs Code.:
UNII:A5E8C36F34
DSSTox Substance ID:DTXSID80170230
Nikkaji Number:J1.286.456F
Wikipedia:Izonsteride
Wikidata:Q15409420
NCI Thesaurus Code:C99548
ChEMBL ID:CHEMBL2104854
Mol file:176975-26-1.mol

Synonyms:Izonsteride;LY 320236;LY-320236

Suppliers and Price of Izonsteride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 28 raw suppliers

Chemical Property of Izonsteride

Chemical Property:

Vapor Pressure:9.33E-15mmHg at 25°C
Boiling Point:608.6°C at 760 mmHg
Flash Point:321.9°C
PSA：86.74000
Density:1.29g/cm³
LogP:5.77250
XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:422.14865580
Heavy Atom Count:29
Complexity:630

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C2C(=CC=C1)SC(=N2)SC3=CC4=C(C=C3)C5(CCC(=O)N(C5CC4)C)C
Isomeric SMILES:CCC1=C2C(=CC=C1)SC(=N2)SC3=CC4=C(C=C3)[C@]5(CCC(=O)N([C@@H]5CC4)C)C
Uses Treatment of prostate cancer (inhibits human type I and II isoforms of 5 -reductase) .

Technology Process of Izonsteride

There total 4 articles about Izonsteride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 176976-44-6
2-chloro-4-ethyl-benzothiazole

: 176976-31-1
(+)-(4aR)-(10bR)-4-methyl-8-mercapto-10b-methyl-1,2,3,4,4a,-5,6,10b-octahydrobenzo[f]quinolin-3-one

: 176975-26-1
izonsteride

Guidance literature:: With potassium carbonate; In N-methyl-acetamide; ethyl acetate;

Reference yield:

: 176976-44-6
2-chloro-4-ethyl-benzothiazole

: 1634-04-4
tert-butyl methyl ether

: 176975-26-1
izonsteride

Guidance literature:: With sodium borohydrid; potassium carbonate; tetra(n-butyl)ammonium hydrogen sulfate; trifluoroacetic anhydride; In water; toluene;

Reference yield:

: 64741-01-1
m-chloroperoxybenzoic acid

: 176976-44-6
2-chloro-4-ethyl-benzothiazole

: (+)-(4aR)-(10bR)-4-methyl-8-methylthio-10b-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one

: 1634-04-4
tert-butyl methyl ether

: 176975-26-1
izonsteride

Guidance literature:: With sodium borohydrid; potassium carbonate; tetra(n-butyl)ammonium hydrogen sulfate; sodium hydrogensulfite; trifluoroacetic anhydride; In dichloromethane; sulfuric acid; water; ethyl acetate; toluene;