4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE

Base Information

• Chemical Name: 4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE
• CAS No.: 61405-25-2
• Molecular Formula: C12H8BrClO3S
• Molecular Weight: 347.617
• Hs Code.: 2909309090
• Mol file: 61405-25-2.mol

Synonyms:4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE

Chemical Property of 4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.618
• Boiling Point: 410.408°C at 760 mmHg
• Flash Point: 202.008°C
• PSA: 51.75000
• Density: 1.633g/cm³
• LogP: 5.24970

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Bromophenoxy)benzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-(4-Bromophenoxy)benzenesulfonyl Chloride is used in the preparation of aryloxybenzenesulfonylhydroxycarboxamides as metalloproteinase inhibitors.

Technology Process of 4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE

There total 3 articles about 4-(4-BROMO-PHENOXY)-BENZENESULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 4-(4-bromophenoxy)-benzenesulfonyl chloride (61405-25-2)

Guidance literature:

Reference yield:

4-Bromodiphenyl ether (101-55-3) → 4-(4-bromophenoxy)-benzenesulfonyl chloride (61405-25-2)

Guidance literature:

With chlorosulphuric acid;

DOI:10.1021/ja01354a045

Reference yield:

→ 4-(4-bromophenoxy)-benzenesulfonyl chloride (61405-25-2)

Guidance literature:

With tetrachloromethane; bromine;

DOI:10.1021/ja01354a045

upstream raw materials:

4-Bromodiphenyl ether

Downstream raw materials:

2(R)1-[4-(Biphenyl₄-yloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid

2(R)-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid

C₂₄H₃₀BrNO₇S

([4-(4-bromo-phenoxy)-benzenesulphonyl]-hydroxycarbamoylmethyl-amino) acetic acid

Refernces

• 1、 -. "Radiolabelled MMP selective compounds". Page/Page column 11. . Retrieved 2009/12/05.
• 2、 -. "Metalloproteinase inhibitors and intermediates useful for their preparation". . . Retrieved 2008/06/13.