2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

Base Information

• Chemical Name: 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE
• CAS No.: 61416-34-0
• Molecular Formula: C10H14ClNO3
• Molecular Weight: 231.679
• Hs Code.: 2923900090
• Mol file: 61416-34-0.mol

Synonyms:2-AMINO-1-(3,4-DIMETHOXY-PHENYL)-ETHANONE HYDROCHLORIDE;2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

Chemical Property of 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

Chemical Property:

• PSA: 61.55000
• LogP: 2.34750

Purity/Quality:

99.90% ^*data from raw suppliers

2-Amino-1-(3,4-dimethoxyphenyl)-1-ethanoneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE

There total 4 articles about 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone (1835-02-5) → 2-amino-1-(3,4-dimethoxy-phenyl)-ethanone; hydrochloride (61416-34-0)

Guidance literature:

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone; With sodium diformamide; In acetonitrile; at 75 ℃; for 8h;

With hydrogenchloride; In water; for 1h; Reflux;

DOI:10.1002/adsc.202000171

Reference yield:

N-(3,4-dimethoxy-phenacyl)-phthalamic acid (871902-52-2) → 2-amino-1-(3,4-dimethoxy-phenyl)-ethanone; hydrochloride (61416-34-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

1-(3,4-dimethoxyphenyl)ethanone (1131-62-0) → 2-amino-1-(3,4-dimethoxy-phenyl)-ethanone; hydrochloride (61416-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: CS₂; bromine

2: Einw_. von alkoh. Salzsaeure auf die additionelle Verbindung in Gegenwart von Silberchlorid bei 20grad

With carbon disulfide; bromine;

upstream raw materials:

hexamethylenetetramine

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

N-(3,4-dimethoxy-phenacyl)-phthalamic acid

1-(3,4-dimethoxyphenyl)ethanone

Downstream raw materials:

C₂₀H₂₂N₂O₆

C₃₀H₃₃N₃O₁₀

2-(Acetylamino)-3',4'-dimethoxyacetophenon

5-amino-1-cyclopentyl-N-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-3-ethyl-1H-pyrazole-4-carboxamide

Refernces

• 1、 Xue, Na,Yang, Xiaochun,Wu, Rui,Chen, Jing,He, Qiaojun,Yang, Bo,Lu, Xiuyang,Hu, Yongzhou. "Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents". . p. 2550 - 2557. Retrieved 2008/09/21.