Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI)

Base Information

Chemical Name:Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI)
CAS No.:612502-28-0
Molecular Formula:C12H18N2
Molecular Weight:190.288
Hs Code.:
Mol file:612502-28-0.mol

Synonyms:Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI);(2S)-2-(2-PHENYLETHYL)PIPERAZINE

Suppliers and Price of Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-2-phenethylpiperazine
10mg
$ 65.00

Crysdot
(S)-2-Phenethylpiperazine 95+%
1g
$ 614.00

Chemenu
(S)-2-PHENETHYL-PIPERAZINE 95%
1g
$ 580.00

American Custom Chemicals Corporation
(S)-2-PHENETHYL-PIPERAZINE 95.00%
5G
$ 2477.48

American Custom Chemicals Corporation
(S)-2-PHENETHYL-PIPERAZINE 95.00%
1G
$ 1264.73

Alichem
(S)-2-Phenethylpiperazine
1g
$ 535.00

Total 6 raw suppliers

Chemical Property of Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI)

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:116-119 °C
Refractive Index:1.511
Boiling Point:313.743°C at 760 mmHg
PKA:9.17±0.40(Predicted)
Flash Point:180.35°C
PSA：24.06000
Density:0.967g/cm³
LogP:1.83820
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-phenethylpiperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI)

There total 4 articles about Piperazine, 2-(2-phenylethyl)-, (2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 134624-92-3
3-(S)-phenethyl-piperazine-2,5-dione

: 612502-28-0,1217452-20-4
(S)-2-phenethylpiperazine

Guidance literature:: 3-(S)-phenethyl-piperazine-2,5-dione; With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Heating / reflux;

With water; sodium sulfate; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Product distribution / selectivity;

Reference yield: 87.0%

: 612503-37-4
(S)-1,4-dibenzyl-2-phenethylpiperazine

: 612502-28-0,1217452-20-4
(S)-2-phenethylpiperazine

Guidance literature:: With ammonium formate; palladium on activated charcoal; In ethanol; for 3h; Heating;
DOI:10.1055/s-2007-983791

Reference yield:

: C₂₈H₃₉BN₂

: 612502-28-0,1217452-20-4
(S)-2-phenethylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₃P; aq. NaOH / (Ph₃P)4Pd / tetrahydrofuran / 22 h / 60 °C

2: 87 percent / ammonium formate / Pd/C / ethanol / 3 h / Heating

With sodium hydroxide; ammonium formate; triphenylphosphine; palladium on activated charcoal; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; 1: Suzuki coupling;
DOI:10.1055/s-2007-983791