N-Hydroxy-3-methyl-pyridine-2-carboxamidine

Base Information

• Chemical Name: N-Hydroxy-3-methyl-pyridine-2-carboxamidine
• CAS No.: 690632-33-8
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.168
• Hs Code.: 2933399990
• Mol file: 690632-33-8.mol

Synonyms:N-Hydroxy-3-methyl-pyridine-2-carboxamidine;SCHEMBL1492852;UQDFGZCCSCDNSO-UHFFFAOYSA-N;(Z)-N'-hydroxy-3-methylpicolinimidamide

Chemical Property of N-Hydroxy-3-methyl-pyridine-2-carboxamidine

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 92-94°C
• Refractive Index: 1.603
• Boiling Point: 298.514ºC at 760 mmHg
• PKA: 13.73±0.50(Predicted)
• Flash Point: 134.337ºC
• PSA: 71.50000
• Density: 1.268g/cm3
• LogP: 1.18480
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 151.074561919
• Heavy Atom Count: 11
• Complexity: 158

Purity/Quality:

98%min ^*data from raw suppliers

3-Methylpyridine-2-amidoxime ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(N=CC=C1)C(=NO)N

Technology Process of N-Hydroxy-3-methyl-pyridine-2-carboxamidine

There total 4 articles about N-Hydroxy-3-methyl-pyridine-2-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ N'-hydroxy-3-methylpyridine-2-carboximidamide (690632-33-8)

Guidance literature:

Reference yield: 93.0%

2-cyano-3-methylpyridine (20970-75-6) → N'-hydroxy-3-methylpicolinimidamide (690632-33-8)

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; In ethanol; at 80 ℃; for 16h;

Reference yield:

2-cyano-3-methylpyridine (20970-75-6) → N'-hydroxy-3-methylpyridine-2-carboximidamide (690632-33-8)

Guidance literature:

With hydroxylamine; sodium methylate; In ethanol; Reflux;

DOI:10.1016/j.bmcl.2012.06.094

upstream raw materials:

2-cyano-3-methylpyridine