7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID

Base Information

• Chemical Name: 7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID
• CAS No.: 7101-63-5
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Hs Code.: 2933990090
• Mol file: 7101-63-5.mol

Synonyms:2,3-Pentamethylen-chinolin-4-carbonsaeure;2,3-Pentamethylen-cinchoninsaeure;

Chemical Property of 7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 3.08E-08mmHg at 25°C
• Refractive Index: 1.647
• Boiling Point: 432.2°C at 760 mmHg
• Flash Point: 215.2°C
• PSA: 50.19000
• Density: 1.244g/cm³
• LogP: 3.20190

Purity/Quality:

98%Min ^*data from raw suppliers

7,8,9,10-Tetrahydro-6H-cyclohepta[b]-quinoline-11-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID

There total 2 articles about 7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) + cycloheptanone (502-42-1) → 2,3-Pentamethylen-chinolin-4-carbonsaeure (7101-63-5)

Guidance literature:

With potassium hydroxide;

Reference yield:

→ 2,3-Pentamethylen-chinolin-4-carbonsaeure (7101-63-5)

Guidance literature:

Isatin, Cycloheptanon;

Reference yield:

morpholine (110-91-8,99108-56-2) + 2,3-Pentamethylen-chinolin-4-carbonsaeure (7101-63-5) → 4-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carbonyl)-morpholine (7101-65-7)

Guidance literature:

Multistep reaction; (i) HCl, PCl₅, (ii) /BRN= 102549/, benzene;

DOI:10.1021/jm00322a008

upstream raw materials:

indole-2,3-dione

cycloheptanone

Downstream raw materials:

4-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carbonyl)-morpholine

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