4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine

Base Information

Chemical Name:4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine
CAS No.:617716-32-2
Molecular Formula:C9H10Cl2N2
Molecular Weight:217.0951
Hs Code.:
DSSTox Substance ID:DTXSID70436155
Wikidata:Q82251385
Mol file:617716-32-2.mol

Synonyms:4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine;617716-32-2;SCHEMBL4429704;DTXSID70436155;AKOS012922941;SB60015;A1-33873

Suppliers and Price of 4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine 97%
1g
$ 681.00

Alichem
4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine
1g
$ 722.40

A1 Biochem Labs
4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine 95%
2.5 g
$ 1100.00

Total 1 raw suppliers

Chemical Property of 4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine

Chemical Property:

Boiling Point:295.0±35.0 °C(Predicted)
PKA:-3.29±0.39(Predicted)
PSA：25.78000
Density:1.351±0.06 g/cm3(Predicted)
LogP:3.22320
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:216.0221037
Heavy Atom Count:13
Complexity:173

Purity/Quality:: 4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(N=C(N=C1Cl)C2CC2)Cl

Technology Process of 4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine

There total 3 articles about 4,6-Dichloro-2-cyclopropyl-5-ethylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 617716-05-9
2-cyclopropyl-5-ethyl-4,6-pyrimidinediol

: 617716-32-2
4,6-dichloro-2-cyclopropyl-5-ethylpyrimidine

Guidance literature:: With N,N-diethylaniline; trichlorophosphate; at 100 ℃;
DOI:10.1016/j.bmcl.2006.01.006

Reference yield:

: 133-13-1
ethyl diethyl malonate

: 617716-32-2
4,6-dichloro-2-cyclopropyl-5-ethylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOEt / ethanol / 60 °C

2: POCl₃; N,N-diethylaniline / 100 °C

With sodium ethanolate; N,N-diethylaniline; trichlorophosphate; In ethanol;
DOI:10.1016/j.bmcl.2006.01.006