Sulfamic acid, 2-ethylphenyl ester (9CI)

Base Information

• Chemical Name: Sulfamic acid, 2-ethylphenyl ester (9CI)
• CAS No.: 691397-24-7
• Molecular Formula: C8H11NO3S
• Molecular Weight: 201.246
• Mol file: 691397-24-7.mol

Synonyms:Sulfamic acid, 2-ethylphenyl ester (9CI)

Chemical Property of Sulfamic acid, 2-ethylphenyl ester (9CI)

Chemical Property:

• PSA: 77.77000
• LogP: 2.61240

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sulfamic acid, 2-ethylphenyl ester (9CI)

There total 3 articles about Sulfamic acid, 2-ethylphenyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

o-Hydroxyethylbenzene (90-00-6) → 2-ethylphenylsulfamate (691397-24-7)

Guidance literature:

With formic acid; isocyanate de chlorosulfonyle; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 3h;

DOI:10.1016/j.tetasy.2004.01.015

Reference yield: 50.0%

2-ethylphenyl sulfurazidate → 2-ethylphenylsulfamate (691397-24-7)

Guidance literature:

With sodium dithionite; In aq. phosphate buffer; dimethyl sulfoxide; pH=8;

DOI:10.1021/jacs.6b11410

Reference yield: 38.0%

(S)-4-methyl-3,4-dihydrobenzo[e][1,2,3]oxathiazine 2,2-dioxide → 2-ethylphenylsulfamate (691397-24-7)

Guidance literature:

In dichloromethane; at -78 ℃; for 13h; pH=6; Catalytic behavior; Molecular sieve;

upstream raw materials:

o-Hydroxyethylbenzene

Downstream raw materials:

(+/-)-N-methyl-N-[α-methyl-(2-methylbenzyl)]-amine

N-benzyl-1-phenylethylamine

3-benzyl-4-methyl-3,4-dihydro-benzo[e][1,2,3]oxathiazine 2,2-dioxide

methyl-[1-(2-trimethylsilanylmethyl-phenyl)-ethyl]-amine

Refernces

• 1、 Dydio, Pawel,Key, Hanna M.,Hayashi, Hiroki,Clark, Douglas S.,Hartwig, John F.. "Chemoselective, enzymatic C-H bond amination catalyzed by a cytochrome P450 containing an Ir(Me)-PIX cofactor". supporting information. p. 1750 - 1753. Retrieved 2017/02/15.
• 2、 Fruit, Corinne,Mueller, Paul. "Asymmetric transfer of nitrenes catalyzed by chiral dirhodium(II) using aromatic sulfamate esters". . p. 1019 - 1026. Retrieved 2007/10/03.