3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

Base Information

Chemical Name:3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine
CAS No.:625100-00-7
Molecular Formula:C8H9BrN2
Molecular Weight:213.077
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30590489
Wikidata:Q72512766
Mol file:625100-00-7.mol

Synonyms:3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine;625100-00-7;3-Bromo-5,6,7,8-tetrahydro-[1,6]naphthyridine;1,6-NAPHTHYRIDINE, 3-BROMO-5,6,7,8-TETRAHYDRO-;SCHEMBL722943;DTXSID30590489;IRZFIOXYROEMPD-UHFFFAOYSA-N;AMY23499;BCP21952;MFCD08059299;SC2711;AKOS015920357;PB26297;AS-54628;SY020081;CS-0053996;5,6,7,8-Tetrahydro-3-bromo-1,6-naphthyridine;A833817;J-511986;3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine, AldrichCPR;3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine?hydrochloride

Suppliers and Price of 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine >95%
500mg
$ 325.00

Matrix Scientific
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine >95%
1g
$ 498.00

Matrix Scientific
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine >95%
5g
$ 1575.00

Crysdot
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine 95%
1g
$ 365.00

Biosynth Carbosynth
3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
500 mg
$ 410.00

Biosynth Carbosynth
3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
100 mg
$ 186.00

Biosynth Carbosynth
3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
50 mg
$ 116.50

Biosynth Carbosynth
3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
25 mg
$ 60.00

Biosynth Carbosynth
3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
250 mg
$ 255.00

Anichem
3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine >95%
1g
$ 250.00

Total 54 raw suppliers

Chemical Property of 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

Chemical Property:

Vapor Pressure:0.00317mmHg at 25°C
Refractive Index:1.585
Boiling Point:283.4 °C at 760 mmHg
PKA:7.16±0.20(Predicted)
Flash Point:125.2 °C
PSA：24.92000
Density:1.503 g/cm³
LogP:1.81860
Storage Temp.:2-8°C(protect from light)
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:211.99491
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC2=C1N=CC(=C2)Br
Uses 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine is a reagent used in the preparation of coagulation factor XIa inhibitors.

Technology Process of 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

There total 1 articles about 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 948306-78-3
C₈H₁₁N₃

: 625100-00-7
3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

Guidance literature:: C₈H₁₁N₃; With hydrogen bromide; sodium nitrite; at 0 ℃;

With hydrogen bromide; copper(I) bromide; at 100 ℃;
DOI:10.1016/j.bmcl.2008.05.069

Reference yield: 100.0%

: 625100-00-7
3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine

: 80957-68-2
5,6,7,8-tetrahydro-1,6-naphthyridine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; for 3.5h; under 2844.39 Torr;
DOI:10.1021/acs.jmedchem.7b01171