Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI)

Base Information

• Chemical Name: Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI)
• CAS No.: 630106-38-6
• Molecular Formula: C12H18O2
• Molecular Weight: 194.27012
• Mol file: 630106-38-6.mol

Synonyms:Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI)

Chemical Property of Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI)

Chemical Property:

• Boiling Point: 215.7±19.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.055±0.06 g/cm3(Predicted)
• LogP: 2.54190

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI)

There total 3 articles about Bicyclo[2.2.1]hept-2-ene-1-carboxylic acid, 4,7,7-trimethyl-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-3-(3-Diazo-1,2,2-trimethyl-cyclopentyl)-acrylic acid methyl ester → (1R,4R)-4,7,7-Trimethyl-bicyclo[2.2.1]hept-2-ene-1-carboxylic acid methyl ester (630106-38-6)

Guidance literature:

(Z)-3-(3-Diazo-1,2,2-trimethyl-cyclopentyl)-acrylic acid methyl ester; In methanol; for 1.25h;

With sulfuric acid; In methanol; Further stages.;

DOI:10.1039/b309329h

Reference yield:

(1S,6S)-6,9,9-Trimethyl-2-nitroso-2-aza-bicyclo[4.2.1]non-4-en-3-one → (1R,4R)-4,7,7-Trimethyl-bicyclo[2.2.1]hept-2-ene-1-carboxylic acid methyl ester (630106-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaOMe / 1.25 h / 0 °C

2.1: methanol / 1.25 h

2.2: H₂SO₄ / methanol

With sodium methylate; In methanol;

DOI:10.1039/b309329h

Reference yield:

→ 4,7,7-Trimethylbicyclo<2.2.1>hept-2-en-1-carbonsaeuremethylester (49852-16-6,630106-38-6)

Guidance literature:

Carbonsaeure (7), Diazomethan;

Downstream raw materials:

methyl 2,7,7-trimethyltricyclo[2.2.1.0^2,6]heptan-2-carboxylate