2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)

Base Information

Chemical Name:2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)
CAS No.:634181-50-3
Molecular Formula:C14H19N
Molecular Weight:201.31
Hs Code.:
Mol file:634181-50-3.mol

Synonyms:2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)

Suppliers and Price of 2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)

Chemical Property:

PSA：3.24000
LogP:3.37640

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI)

There total 3 articles about 2-Azabicyclo[3.1.0]hexane,6-ethyl-1-methyl-2-phenyl-,(1R,5S,6S)-rel-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 32916-51-1
cyclopentylmagnesium chloride

: N-hex-3-enyl-N-phenyl-acetamide

: ((Z)-Hex-3-enyl)-phenyl-amine

: ((Z)-Hex-3-enyl)-(6-methyl-bicyclo[3.1.0]hex-6-yl)-phenyl-amine

: (1-Cyclopentyl-ethyl)-((Z)-hex-3-enyl)-phenyl-amine

: 634181-50-3,634181-51-4
(1R,5S,6S)-6-Ethyl-1-methyl-2-phenyl-2-aza-bicyclo[3.1.0]hexane

Guidance literature:: With titanium(IV) isopropylate; In diethyl ether; toluene; at 20 ℃; for 0.25h;
DOI:10.1039/b306719j

Reference yield: 24.0%

: 32916-51-1
cyclopentylmagnesium chloride

: N-((E)-hex-3-enyl)-N-phenylacetamide

: (E)-N-(hex-3-en-1-yl)aniline

: ((E)-Hex-3-enyl)-(6-methyl-bicyclo[3.1.0]hex-6-yl)-phenyl-amine

: (E)-N-(1-cyclopentylethyl)-N-(hex-3-en-1-yl)aniline

: 634181-50-3,634181-51-4
(1R,5S,6R)-6-Ethyl-1-methyl-2-phenyl-2-aza-bicyclo[3.1.0]hexane

Guidance literature:: With titanium(IV) isopropylate; In diethyl ether; at 20 ℃;
DOI:10.1039/b306719j

Reference yield:

: 1610026-56-6
N-((E)-hex-3-enyl)-N-phenylethanethioamide

: 32916-51-1
cyclopentylmagnesium chloride

: 634181-50-3,634181-51-4
(1R*,5S*,6R*)-6-ethyl-1-methyl-2-phenyl-2-azabicyclo[3.1.0]hexane

: (E)-N-(hex-3-en-1-yl)aniline

: (E)-N-(1-cyclopentylethyl)-N-(hex-3-en-1-yl)aniline

Guidance literature:: N-((E)-hex-3-enyl)-N-phenylethanethioamide; cyclopentylmagnesium chloride; With titanium(IV) isopropylate; In diethyl ether; tert-butyl methyl ether; at 20 ℃; for 1h; Inert atmosphere;

With ammonia; In diethyl ether; tert-butyl methyl ether; water; diastereoselective reaction;
DOI:10.1016/j.tet.2014.04.006