Isophthalaldehydic acid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI)

Base Information

• Chemical Name: Isophthalaldehydic acid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI)
• CAS No.: 647013-80-7
• Molecular Formula: C₁₁H₁₂O₅
• Molecular Weight: 224.213
• Mol file: 647013-80-7.mol

Synonyms:Isophthalaldehydicacid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI)

Chemical Property of Isophthalaldehydic acid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI)

Chemical Property:

• Melting Point: 148 °C
• Boiling Point: 323.4±42.0 °C(Predicted)
• PKA: 7.84±0.33(Predicted)
• PSA: 83.83000
• Density: 1.331±0.06 g/cm3(Predicted)
• LogP: 1.31370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isophthalaldehydic acid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI)

There total 3 articles about Isophthalaldehydic acid, 2,6-dihydroxy-4,5-dimethyl-, methyl ester (5CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dihydroxy-3,4-dimethoxybenzoic acid methyl ester (32749-10-3) → 3-formyl-2,6-dihydroxy-4,5-dimethyl-benzoic acid methyl ester (647013-80-7)

Guidance literature:

With hydrogenchloride; diethyl ether; Erwaermen des Reaktionsprodukts mit Wasser;

DOI:10.1039/jr9490003038

Reference yield:

4,5-dimethylresorcinol (527-55-9) → 3-formyl-2,6-dihydroxy-4,5-dimethyl-benzoic acid methyl ester (647013-80-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydrogencarbonate; glycerol / 150 °C

2: diethyl ether

3: hydrogen chloride; diethyl ether / Erwaermen des Reaktionsprodukts mit Wasser

With hydrogenchloride; diethyl ether; potassium hydrogencarbonate; glycerol;

DOI:10.1039/jr9490003038

Reference yield:

2,6-dihydroxy-3,4-dimethyl-benzoic acid (647014-67-3) → 3-formyl-2,6-dihydroxy-4,5-dimethyl-benzoic acid methyl ester (647013-80-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: hydrogen chloride; diethyl ether / Erwaermen des Reaktionsprodukts mit Wasser

With hydrogenchloride; diethyl ether;

DOI:10.1039/jr9490003038

upstream raw materials:

2,6-dihydroxy-3,4-dimethoxybenzoic acid methyl ester

4,5-dimethylresorcinol

2,6-dihydroxy-3,4-dimethyl-benzoic acid