2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI)

Base Information

• Chemical Name: 2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI)
• CAS No.: 652150-92-0
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 652150-92-0.mol

Synonyms:2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI)

Chemical Property of 2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI)

Chemical Property:

• PSA: 35.53000
• LogP: 2.15480

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI)

There total 3 articles about 2-Oxetanone,3-ethyl-4-[(phenylmethoxy)methyl]-,(3R,4R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

butyryl bromide (5856-82-6) + benzyloxyacetoaldehyde (60656-87-3) → (3R,4R)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + (3S,4S)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + 4-benzyloxymethyl-3-ethyl-oxetan-2-one (652150-92-0)

Guidance literature:

With (S,S)-ArSO₂NCH(i-Pr)CH₂N(CH₂CF₃)CH₂CH(i-Pr)NSO₂CF₃*AlMe; N-ethyl-N,N-diisopropylamine; In various solvent(s); at -25 ℃; for 14h; Title compound not separated from byproducts;

DOI:10.1021/ja0391208

Reference yield:

butyryl bromide (5856-82-6) + benzyloxyacetoaldehyde (60656-87-3) → (3R,4R)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + (3S,4S)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + 4-benzyloxymethyl-3-ethyl-oxetan-2-one (652150-92-0)

Guidance literature:

With (S,S)-ArSO₂NCH(i-Pr)CH₂N(CH₂CF₃)CH₂CH(i-Pr)NSO₂CF₃*AlMe; N-ethyl-N,N-diisopropylamine; In various solvent(s); at -25 ℃; for 14h; Title compound not separated from byproducts;

DOI:10.1021/ja0391208

Reference yield:

butyryl bromide (5856-82-6) + benzyloxyacetoaldehyde (60656-87-3) → (3R,4R)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + (3S,4S)-4-(benzyloxymethyl)-3-ethyloxetan-2-one (652150-92-0) + 4-benzyloxymethyl-3-ethyl-oxetan-2-one (652150-92-0)

Guidance literature:

With (S,S)-ArSO₂NCH(i-Pr)CH₂N(CH₂CF₃)CH₂CH(i-Pr)NSO₂CF₃*AlMe; N-ethyl-N,N-diisopropylamine; In various solvent(s); at -25 ℃; for 14h; Title compound not separated from byproducts;

DOI:10.1021/ja0391208

upstream raw materials:

butyryl bromide

benzyloxyacetoaldehyde