4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL

Base Information

• Chemical Name: 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL
• CAS No.: 70588-04-4
• Molecular Formula: C9H2D17N2O*
• Molecular Weight: 188.36
• Mol file: 70588-04-4.mol

Synonyms:TEMPAMINE-D17;4-AMINO-TEMPO-PIPERIDINYL-D17;4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL;4-Amino-2,2,6,6-tetramethylpiperidine-d17-1-oxyl, Tempamine-d17

Chemical Property of 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL

Chemical Property:

• Melting Point: 38-41 °C(lit.)
• PSA: 29.26000
• LogP: 1.95040

Purity/Quality:

99%min ^*data from raw suppliers

4-Amino-2,2,6,6-tetramethylpiperidine-d17-1-oxyl ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Amino-2,2,6,6-tetramethylpiperidine-d17-1-oxyl (CAS# 70588-04-4) is a useful isotopically labeled research compound.

Technology Process of 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL

There total 3 articles about 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE-D17-1-OXYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

4-acetamino-perdeutero-2,2,6,6-tetramethylpiperidine-N-oxyl (14691-89-5) → 4-amino-perdeutero-2,2,6,6-tetramethylpiperidine-N-oxyl (70588-04-4)

Guidance literature:

With potassium hydroxide;

DOI:10.1016/0022-2364(80)90056-6

Reference yield:

4-hydroxyimino-1H-perdeutero-2,2,6,6-tetramethylpiperidine → 4-amino-perdeutero-2,2,6,6-tetramethylpiperidine-N-oxyl (70588-04-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 69.5 percent / PtO₂ / 12 h / 25 °C / 300.02 Torr

2: 60 percent / H₂O₂

3: 49 percent / 15percent KOH

With platinum(IV) oxide; potassium hydroxide; dihydrogen peroxide;

DOI:10.1016/0022-2364(80)90056-6

Reference yield:

4-acetamino-1H-perdeutero-2,2,6,6-tetramethylpiperidine (73322-05-1) → 4-amino-perdeutero-2,2,6,6-tetramethylpiperidine-N-oxyl (70588-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / H₂O₂

2: 49 percent / 15percent KOH

With potassium hydroxide; dihydrogen peroxide;

DOI:10.1016/0022-2364(80)90056-6

upstream raw materials:

4-acetamino-perdeutero-2,2,6,6-tetramethylpiperidine-N-oxyl

4-acetamino-1H-perdeutero-2,2,6,6-tetramethylpiperidine

Downstream raw materials:

1-(2,2,6,6-tetramethylpiperidine-1-oxyl-⁽²⁾H₁₇-4-carbamoylpropyl)-5-ethyl-5-phenylbarbituric acid

Refernces