(R)-(+)-2-(ALPHA-METHYLBENZYLAMINO)-5-NITROPYRIDINE

Base Information

• Chemical Name: (R)-(+)-2-(ALPHA-METHYLBENZYLAMINO)-5-NITROPYRIDINE
• CAS No.: 64138-65-4
• Molecular Formula: C₁₃H₁₃N₃O₂
• Molecular Weight: 243.265
• Mol file: 64138-65-4.mol

Synonyms:2-Pyridinamine,5-nitro-N-(1-phenylethyl)-, (R)-; (+)-2-(a-Methylbenzylamino)-5-nitropyridine

Chemical Property of (R)-(+)-2-(ALPHA-METHYLBENZYLAMINO)-5-NITROPYRIDINE

Chemical Property:

• Melting Point: 83°C
• Refractive Index: 146.5 ° (C=2, CHCl3)
• Boiling Point: 395.9oC at 760 mmHg
• PKA: 2.74±0.10(Predicted)
• Flash Point: 193.2oC
• PSA: 70.74000
• Density: 1.267g/cm3
• LogP: 3.75910
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Nitro-N-[(1R)-1-phenylethyl]pyridin-2-amine ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-(+)-2-(ALPHA-METHYLBENZYLAMINO)-5-NITROPYRIDINE

There total 2 articles about (R)-(+)-2-(ALPHA-METHYLBENZYLAMINO)-5-NITROPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-1-phenyl-ethyl-amine (3886-69-9) + potassium 5-nitropyridine-2-sulfonate → 2-(α-methylbenzylamino)-5-nitropyridine (64138-65-4,84249-39-8)

Guidance literature:

In water; at 23 ℃; for 20h;

DOI:10.1039/b305620a

Reference yield:

→ 2-(α-methylbenzylamino)-5-nitropyridine (64138-65-4,84249-39-8)

Guidance literature:

entspr. Amin, 2-Chloro-5-nitropyridin;

upstream raw materials:

(R)-1-phenyl-ethyl-amine

Refernces

• 1、 Bakke, Jan M.,Sletvold, Ingrid. "Substitution reactions of 5-nitropyridine-2-sulfonic acid. A new pathway to 2,5-disubstituted pyridines". . p. 2710 - 2715. Retrieved 2007/10/03.