4-Methoxy-2,5-dimethylbenzonitrile

Base Information

Chemical Name:4-Methoxy-2,5-dimethylbenzonitrile
CAS No.:64400-49-3
Molecular Formula:C10H11 N O
Molecular Weight:161.203
Hs Code.:2926909090
DSSTox Substance ID:DTXSID30391130
Nikkaji Number:J2.607.620J
Wikidata:Q82188380
Mol file:64400-49-3.mol

Synonyms:4-methoxy-2,5-dimethylbenzonitrile;64400-49-3;2,5-Dimethyl-p-anisonitrile;2,5-Dimethyl-4-methoxybenzonitrile;4-methoxy-2,5-dimethyl-benzonitrile;SCHEMBL13387367;DTXSID30391130;AKOS006243106;TS-02148;CS-0377843

Suppliers and Price of 4-Methoxy-2,5-dimethylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Dimethyl-p-anisonitrile
1g
$ 310.00

TRC
2,5-Dimethyl-p-anisonitrile
500mg
$ 200.00

Sigma-Aldrich
2,5-DIMETHYL-PARA-ANISONITRILE Aldrich
1g
$ 144.00

Matrix Scientific
2,5-Dimethyl-p-anisonitrile 97%
1g
$ 165.00

Crysdot
4-Methoxy-2,5-dimethylbenzonitrile 97%
5g
$ 345.00

Atlantic Research Chemicals
2,5-Dimethyl-p-anisonitrile 95%
1gm:
$ 74.23

Alichem
2,5-Dimethyl-4-methoxybenzonitrile
1g
$ 1549.60

Alichem
2,5-Dimethyl-4-methoxybenzonitrile
500mg
$ 806.85

Alichem
2,5-Dimethyl-4-methoxybenzonitrile
250mg
$ 504.00

Total 3 raw suppliers

Chemical Property of 4-Methoxy-2,5-dimethylbenzonitrile

Chemical Property:

PSA：33.02000
LogP:2.18368
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dimethyl-p-anisonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1OC)C)C#N

Technology Process of 4-Methoxy-2,5-dimethylbenzonitrile

There total 5 articles about 4-Methoxy-2,5-dimethylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1706-11-2
2,5-Dimethyl-anisol

: (3,5-bis(trifluoromethyl)phenyl)(cyano)-l3-iodanyl trifluoromethanesulfonate

: 64400-49-3
4-methoxy-2,5-dimethylbenzonitrile

Guidance literature:: With iron(II) acetate; In 1,2-dichloro-ethane; at 30 ℃; for 4h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1002/anie.201309791

Reference yield: 97.0%

: 75-05-8,26809-02-9
acetonitrile

: 1706-11-2
2,5-Dimethyl-anisol

: 64400-49-3
4-methoxy-2,5-dimethylbenzonitrile

Guidance literature:: 2,5-Dimethyl-anisol; With N-iodo-succinimide; oxygen; ytterbium(III) triflate; In acetonitrile; at 150 ℃; for 0.5h;

acetonitrile; With 2,2,6,6-tetramethyl-piperidine-N-oxyl; 1,10-Phenanthroline; copper(II) nitrate trihydrate; 1,1,1,2,2,2-hexamethyldisilane; oxygen; at 150 ℃; for 60h;
DOI:10.1021/acs.orglett.5b00886