C₂₂H₁₉ClN₆O₄S

Base Information

• Chemical Name: C₂₂H₁₉ClN₆O₄S
• CAS No.: 441797-61-1
• Molecular Formula: C₂₂H₁₉ClN₆O₄S
• Molecular Weight: 498.95
• Mol file: 441797-61-1.mol

Synonyms:

Chemical Property of C₂₂H₁₉ClN₆O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₁₉ClN₆O₄S

There total 6 articles about C₂₂H₁₉ClN₆O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (2-methoxyphenoxy) ethanoate (38768-62-6) → C22H19ClN6O4S (441797-61-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 5 h / 40 - 45 °C

1.2: 24 h / 20 - 32 °C

2.1: sodium / methanol / 18 h / 0 - 20 °C

2.2: 4 h / 20 °C

3.1: trichlorophosphate / N,N-dimethyl-aniline / 2 h / 130 °C

4.1: dimethyl sulfoxide / 48 h / 20 °C

With sodium; sodium hydride; trichlorophosphate; In tetrahydrofuran; methanol; dimethyl sulfoxide; N,N-dimethyl-aniline; mineral oil;

DOI:10.1021/jm3009103

Reference yield:

(2-methoxyphenoxy)-malonic acid dimethyl ester (150726-89-9) → C22H19ClN6O4S (441797-61-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium / methanol / 18 h / 0 - 20 °C

1.2: 4 h / 20 °C

2.1: trichlorophosphate / N,N-dimethyl-aniline / 2 h / 130 °C

3.1: dimethyl sulfoxide / 48 h / 20 °C

With sodium; trichlorophosphate; In methanol; dimethyl sulfoxide; N,N-dimethyl-aniline;

DOI:10.1021/jm3009103

Reference yield:

(2-methoxyphenoxy)acetic acid (1878-85-9) → C22H19ClN6O4S (441797-61-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: thionyl chloride / 3 h / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 5 h / 40 - 45 °C

2.2: 24 h / 20 - 32 °C

3.1: sodium / methanol / 18 h / 0 - 20 °C

3.2: 4 h / 20 °C

4.1: trichlorophosphate / N,N-dimethyl-aniline / 2 h / 130 °C

5.1: dimethyl sulfoxide / 48 h / 20 °C

With thionyl chloride; sodium; sodium hydride; trichlorophosphate; In tetrahydrofuran; methanol; dimethyl sulfoxide; N,N-dimethyl-aniline; mineral oil;

DOI:10.1021/jm3009103

upstream raw materials:

methyl (2-methoxyphenoxy) ethanoate

(2-methoxyphenoxy)-malonic acid dimethyl ester

5-(2-methoxy-phenoxy)-2-pyrazin-2-yl-pyrimidine-4,6-diol

(2-methoxyphenoxy)acetic acid

Downstream raw materials:

C₂₄H₂₄N₆O₆S

C₂₈H₂₅BrN₈O₆S