parabactin azide

Base Information

• Chemical Name: parabactin azide
• CAS No.: 105430-57-7
• Molecular Formula: C₃₂H₃₅N₇O₉
• Molecular Weight: 661.671
• Mol file: 105430-57-7.mol

Synonyms:

Chemical Property of parabactin azide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of parabactin azide

There total 4 articles about parabactin azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethyl 4-azido-2-hydroxybenzimidate hydrochloride (105430-52-2) + N1,N8-bis(2,3-dihydroxybenzoyl)-M4-(L-threonyl)spermidine hydrobromide (82247-46-9) → parabactin azide (105430-57-7)

Guidance literature:

In methanol; for 20h; Heating;

DOI:10.1021/jo00377a026

Reference yield:

2-hydroxy-4-nitro-benzonitrile (39835-14-8) → parabactin azide (105430-57-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 84 percent / HCl(gas) / 48 h / Ambient temperature

2: H₂ / 10percent Pd/C / ethanol / 7 h

3: 1.) isoamyl nitrite, acetic acid, 2.) NaN₃ / 1.) ethyl acetate, 3 h, 2.) ethyl acetate, 3 h

4: 76 percent / methanol / 20 h / Heating

With hydrogenchloride; sodium azide; hydrogen; acetic acid; isopentyl nitrite; palladium on activated charcoal; In methanol; ethanol;

DOI:10.1021/jo00377a026

Reference yield:

ethyl 2-hydroxy-4-nitrobenzimidate hydrochloride (105430-50-0) → parabactin azide (105430-57-7)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / 10percent Pd/C / ethanol / 7 h

2: 1.) isoamyl nitrite, acetic acid, 2.) NaN₃ / 1.) ethyl acetate, 3 h, 2.) ethyl acetate, 3 h

3: 76 percent / methanol / 20 h / Heating

With sodium azide; hydrogen; acetic acid; isopentyl nitrite; palladium on activated charcoal; In methanol; ethanol;

DOI:10.1021/jo00377a026

upstream raw materials:

ethyl 4-azido-2-hydroxybenzimidate hydrochloride

N¹,N⁸-bis(2,3-dihydroxybenzoyl)-M⁴-(L-threonyl)spermidine hydrobromide

2-hydroxy-4-nitro-benzonitrile

ethyl 4-amino-2-hydroxybenzimidate hydrochloride

Refernces