2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid

Base Information

Chemical Name:2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid
CAS No.:324028-06-0
Molecular Formula:C₁₁H₁₀F₃NO₃
Molecular Weight:261.201
Hs Code.:2924299090
DSSTox Substance ID:DTXSID30692972
Mol file:324028-06-0.mol

Synonyms:324028-06-0;2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid;2-Acetylamino-3-(3,4,5-trifluorophenyl)-propionic acid;2-Acetylamino-3-(3,4,5-trifluoro-phenyl)-propionic acid;DTXSID30692972;N-ACETYL-3-(3,4,5-TRIFLUORO-PHENYL)-DL-ALANINE;AKOS013465853;N-Acetyl-3,4,5-trifluorophenylalanine;A5811;FT-0714782;Q-102237;2-Acetylamino-3-(3,4,5-trifluorophenyl)propanoic acid

Suppliers and Price of 2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Acetamido-3-(3,4,5-trifluorophenyl)propanoicacid 97%
10g
$ 604.00

Crysdot
2-Acetamido-3-(3,4,5-trifluorophenyl)propanoicacid 97%
5g
$ 377.00

Chemenu
2-acetamido-3-(3,4,5-trifluorophenyl)propanoicacid 97%
5g
$ 356.00

Chemenu
2-acetamido-3-(3,4,5-trifluorophenyl)propanoicacid 97%
10g
$ 570.00

American Custom Chemicals Corporation
N-ACETYL-3-(3,4,5-TRIFLUOROPHENYL)-DL ALANINE 95.00%
1G
$ 625.00

American Custom Chemicals Corporation
N-ACETYL-3-(3,4,5-TRIFLUOROPHENYL)-DL ALANINE 95.00%
5MG
$ 497.23

Alichem
2-Acetamido-3-(3,4,5-trifluorophenyl)propanoicacid
10g
$ 511.68

Total 22 raw suppliers

Chemical Property of 2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid

Chemical Property:

Vapor Pressure:9.23E-09mmHg at 25°C
Refractive Index:1.503
Boiling Point:446.7 °C at 760 mmHg
Flash Point:223.9 °C
PSA：66.40000
Density:1.409 g/cm³
LogP:1.62660
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:261.06127767
Heavy Atom Count:18
Complexity:315

Purity/Quality:

97% ^*data from raw suppliers

2-Acetamido-3-(3,4,5-trifluorophenyl)propanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CC1=CC(=C(C(=C1)F)F)F)C(=O)O

Technology Process of 2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid

There total 3 articles about 2-Acetamido-3-(3,4,5-trifluorophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 324028-00-4
2-acetylamino-2-(3,4,5-trifluoro-benzyl)-malonic acid

: 324028-06-0
acetyl-DL-3,4,5-trifluorophenylalanine

Guidance literature:: In xylene; at 139 ℃; for 2h;
DOI:10.1246/bcsj.73.2531

Reference yield:

: 220141-72-0
3,4,5-trifluorobenzyl bromide

: 324028-06-0
acetyl-DL-3,4,5-trifluorophenylalanine

Guidance literature:: Multi-step reaction with 3 steps

1: Na; C₂H₅OH / 2 h / Heating

2: NaOH; HCl / methanol / 3 h / 40 °C

3: xylene / 2 h / 139 °C

With hydrogenchloride; sodium hydroxide; ethanol; sodium; In methanol; xylene;
DOI:10.1246/bcsj.73.2531

Reference yield:

: 324027-94-3
diethyl 2-acetamido-2-(3,4,5-trifluorobenzyl)malonate

: 324028-06-0
acetyl-DL-3,4,5-trifluorophenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH; HCl / methanol / 3 h / 40 °C

2: xylene / 2 h / 139 °C

With hydrogenchloride; sodium hydroxide; In methanol; xylene;
DOI:10.1246/bcsj.73.2531