1-(4-ethylphenyl)-1-propanol

Base Information

• Chemical Name: 1-(4-ethylphenyl)-1-propanol
• CAS No.: 74532-88-0
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.247
• Mol file: 74532-88-0.mol

Synonyms:

Chemical Property of 1-(4-ethylphenyl)-1-propanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-ethylphenyl)-1-propanol

There total 1 articles about 1-(4-ethylphenyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-(4-ethylphenyl)-1-propanone (27465-51-6) → 1-(4-ethylphenyl)-1-propanol (1208986-88-2,74532-88-0)

Guidance literature:

1-(4-ethylphenyl)-1-propanone; With 2.6-dimethylphenol; Triethoxysilane; diethylzinc; In tetrahydrofuran; hexane; at 60 ℃; for 0.5h; Inert atmosphere;

With sodium hydroxide; In tetrahydrofuran; methanol; hexane; water; at 0 ℃; for 1h;

DOI:10.1002/asia.201000317

Reference yield: 87.0%

1-(4-ethylphenyl)-1-propanol (1208986-88-2,74532-88-0) → 4-[(1E)-prop-1-en-1-yl]-1-ethylbenzene

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 5h; Reflux; Inert atmosphere;

DOI:10.1002/anie.201208906

Reference yield:

1-(4-ethylphenyl)-1-propanol (1208986-88-2,74532-88-0) → C16H29NO2SSi

Guidance literature:

Multi-step reaction with 3 steps

1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux; Inert atmosphere

2.1: palladium on activated charcoal; hydrogen / ethanol / 20 °C / Inert atmosphere

3.1: neat (no solvent) / 0.5 h / -10 °C / Schlenk technique; Inert atmosphere; Molecular sieve

3.2: 255 / 2 h / -10 °C / Schlenk technique; Inert atmosphere; Molecular sieve

With palladium on activated charcoal; hydrogen; toluene-4-sulfonic acid; In ethanol; toluene;

DOI:10.1002/anie.201208906

upstream raw materials:

1-(4-ethylphenyl)-1-propanone

Downstream raw materials:

p-(n-propyl)ethylbenzene