C₅₈H₈₈N₁₂O₁₃

Base Information

• Chemical Name: C₅₈H₈₈N₁₂O₁₃
• CAS No.: 1367370-32-8
• Molecular Formula: C₅₈H₈₈N₁₂O₁₃
• Molecular Weight: 1161.41
• Mol file: 1367370-32-8.mol

Synonyms:

Chemical Property of C₅₈H₈₈N₁₂O₁₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₈H₈₈N₁₂O₁₃

There total 9 articles about C₅₈H₈₈N₁₂O₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N3(α-aminoisobutyric acid)4OtBu (1187839-02-6) → C58H88N12O13 (1367370-32-8)

Guidance literature:

Multi-step reaction with 5 steps

1: palladium on activated charcoal; hydrogen / methanol

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / Inert atmosphere

4: acetic anhydride / 2 h / 120 °C / Inert atmosphere

5: acetonitrile / 72 h / 90 °C / Inert atmosphere

With palladium on activated charcoal; hydrogen; acetic anhydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In methanol; dichloromethane; acetonitrile;

DOI:10.1039/c2cc00060a

Reference yield:

Cbz(L-Phe)(α-aminoisobutyric acid)4OtBu (1187839-07-1) → C58H88N12O13 (1367370-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / Inert atmosphere

2: acetic anhydride / 2 h / 120 °C / Inert atmosphere

3: acetonitrile / 72 h / 90 °C / Inert atmosphere

With acetic anhydride; trifluoroacetic acid; In dichloromethane; acetonitrile;

DOI:10.1039/c2cc00060a

Reference yield:

Cbz(L-Phe)Aib4OH (1187839-12-8) → C58H88N12O13 (1367370-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride / 2 h / 120 °C / Inert atmosphere

2: acetonitrile / 72 h / 90 °C / Inert atmosphere

With acetic anhydride; In acetonitrile;

DOI:10.1039/c2cc00060a

upstream raw materials:

N₃(α-aminoisobutyric acid)₄OtBu

Cbz(L-Phe)(α-aminoisobutyric acid₎₄OtBu

Cbz(L-Phe)Aib₄OH

N₃Aib₄-OH