C₁₄H₁₉NO₃

Base Information

• Chemical Name: C₁₄H₁₉NO₃
• CAS No.: 1082741-08-9
• Molecular Formula: C₁₄H₁₉NO₃
• Molecular Weight: 249.31
• Mol file: 1082741-08-9.mol

Synonyms:

Chemical Property of C₁₄H₁₉NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₉NO₃

There total 1 articles about C₁₄H₁₉NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H19NO3 (1082741-07-8) → C14H19NO3 (1082741-08-9)

Guidance literature:

With aluminum (III) chloride; sodium chloride; at 135 ℃;

DOI:10.1016/j.ijpharm.2010.06.036

Reference yield:

C14H19NO3 (1082741-08-9) → C20H29N6O5P (1082741-33-0)

Guidance literature:

Multi-step reaction with 9 steps

1.1: palladium on activated charcoal; methanesulfonic acid; hydrogen; acetic acid / ethanol; ethyl acetate

2.1: potassium hydroxide / methanol; water / 3.5 h / 100 °C

3.1: pyridine; dmap / 144 h / Heating

4.1: ethyl methyl ether; water / 16 h / 125 °C

5.1: tetrabutyl-ammonium chloride; N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 8.5 h / 110 °C

5.2: 15.25 h / 0 °C

6.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.5 h / 20 °C

6.2: 17 h / 70 °C

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2.5 h / 20 °C

8.1: ammonia / methanol / 15 h / 85 °C / Autoclave

9.1: trimethylsilyl bromide / acetonitrile / 16 h / 20 °C

With pyridine; dmap; methanesulfonic acid; trimethylsilyl bromide; palladium on activated charcoal; tetrabutyl ammonium fluoride; tetrabutyl-ammonium chloride; ammonia; hydrogen; acetic acid; N,N-dimethyl-aniline; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium hydroxide; trichlorophosphate; In tetrahydrofuran; methanol; ethanol; ethyl methyl ether; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/j.ijpharm.2010.06.036

Reference yield:

C14H19NO3 (1082741-08-9) → C24H35ClN5O5P

Guidance literature:

Multi-step reaction with 7 steps

1.1: palladium on activated charcoal; methanesulfonic acid; hydrogen; acetic acid / ethanol; ethyl acetate

2.1: potassium hydroxide / methanol; water / 3.5 h / 100 °C

3.1: pyridine; dmap / 144 h / Heating

4.1: ethyl methyl ether; water / 16 h / 125 °C

5.1: tetrabutyl-ammonium chloride; N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 8.5 h / 110 °C

5.2: 15.25 h / 0 °C

6.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.5 h / 20 °C

6.2: 17 h / 70 °C

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2.5 h / 20 °C

With pyridine; dmap; methanesulfonic acid; palladium on activated charcoal; tetrabutyl ammonium fluoride; tetrabutyl-ammonium chloride; hydrogen; acetic acid; N,N-dimethyl-aniline; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium hydroxide; trichlorophosphate; In tetrahydrofuran; methanol; ethanol; ethyl methyl ether; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/j.ijpharm.2010.06.036

upstream raw materials:

C₁₄H₁₉NO₃

Downstream raw materials:

C₂₀H₂₉N₆O₅P

C₁₄H₂₁NO₂

C₁₂H₁₉NO

C₂₄H₃₇N₆O₅P