2,6-Diamino-3,5-diiodopyridine

Base Information

• Chemical Name: 2,6-Diamino-3,5-diiodopyridine
• CAS No.: 58372-55-7
• Molecular Formula: C5H5 I2 N3
• Molecular Weight: 360.92
• Mol file: 58372-55-7.mol

Synonyms:Pyridine,2,6-diamino-3,5-diiodo- (6CI); 3,5-Diiodo-2,6-pyridinediamine; NSC 52113

Chemical Property of 2,6-Diamino-3,5-diiodopyridine

Chemical Property:

• Vapor Pressure: 2.92E-07mmHg at 25°C
• Boiling Point: 420°Cat760mmHg
• Flash Point: 207.8°C
• PSA: 64.93000
• Density: 2.747g/cm³
• LogP: 2.61760

Purity/Quality:

99% ^*data from raw suppliers

3,5-Diiodo-pyridine-2,6-diamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Diamino-3,5-diiodopyridine

There total 2 articles about 2,6-Diamino-3,5-diiodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2.6-diaminopyridine (141-86-6) → 3,5-diiodo-2,6-pyridinediamine (58372-55-7)

Guidance literature:

With N-iodo-succinimide; In N,N-dimethyl-formamide; at -30 - 20 ℃;

DOI:10.1016/S0040-4020(03)00073-5

Reference yield: 86.0%

3,5-diaminopyridine (4318-78-9) → 3,5-diiodo-2,6-pyridinediamine (58372-55-7)

Guidance literature:

With N-Iodosuccinamide; In N,N-dimethyl-formamide;

DOI:10.1021/ja067410t

Reference yield: 90.0%

3,5-diiodo-2,6-pyridinediamine (58372-55-7) + phenylacetylene (536-74-3) → 3,5-bis(phenylethynyl)-2,6-pyridinediamine (288254-74-0)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/S0040-4020(03)00073-5

upstream raw materials:

2.6-diaminopyridine

3,5-diaminopyridine

Downstream raw materials:

3,5-bis(phenylethynyl)-2,6-pyridinediamine

2,6-diphenyl-1,7-dihydrodipyrrolo[2,3-b:3’,2’-e]pyridine

Refernces

• 1、 Blight, Barry A.,Camara-Campos, Amaya,Djurdjevic, Smilja,Kaller, Martin,Leigh, David A.,McMillan, Fiona M.,McNab, Hamish,Slawin, Alexandra M. Z.. "AAA-DDD triple hydrogen bond complexes". . p. 14116 - 14122. Retrieved 2009.
• 2、 Koradin, Christopher,Dohle, Wolfgang,Rodriguez, Alain L.,Schmid, Bertram,Knochel, Paul. "Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases". . p. 1571 - 1587. Retrieved 2007/10/03.