C20 CERAMIDE

Base Information

• Chemical Name: C20 CERAMIDE
• CAS No.: 123482-93-9
• Molecular Formula: C₃₈H₇₅NO₃
• Molecular Weight: 594.018
• Mol file: 123482-93-9.mol

Synonyms:

Chemical Property of C20 CERAMIDE

Chemical Property:

• Melting Point: 89-90°C
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

C20 Ceramide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: C20 Ceramide (d18:1/20:0) has been used: as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2) as a standard for the quantitation of sphingolipid metabolites to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction

Technology Process of C20 CERAMIDE

There total 2 articles about C20 CERAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,4E)-2-amino-4-octadecene-1,3-diol (123-78-4) + eicosanoic acid p-nitrophenyl ester → N-arachidoyl-D-erythro-sphingosine (7344-02-7,123482-93-9)

Guidance literature:

With dmap; In tetrahydrofuran; at 40 ℃; for 12h;

DOI:10.1021/jm00012a018

Reference yield:

→ Arachidyl-N-sphingosin (315710-08-8,123482-93-9)

Guidance literature:

Reference yield:

N-arachidoyl-D-erythro-sphingosine (7344-02-7,123482-93-9) → C64H93NO4

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane; tetrahydrofuran

2: pyridine / toluene

With pyridine; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1021/acs.bioconjchem.6b00177

upstream raw materials:

(2S,3R,4E)-2-amino-4-octadecene-1,3-diol

Refernces

• 1、 Morita,Motoki,Akimoto,Natori,Sakai,Sawa,Yamaji,Koezuka,Kobayashi,Fukushima. "Structure-activity relationship of α-galactosylceramides against b16- bearing mice". . p. 2176 - 2187. Retrieved 2007/10/02.