C₁₉H₁₇N₃O₂

Base Information

• Chemical Name: C₁₉H₁₇N₃O₂
• CAS No.: 1354201-42-5
• Molecular Formula: C₁₉H₁₇N₃O₂
• Molecular Weight: 319.363
• Mol file: 1354201-42-5.mol

Synonyms:

Chemical Property of C₁₉H₁₇N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₁₇N₃O₂

There total 9 articles about C₁₉H₁₇N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C35H34F17N3O2Si → C19H17N3O2 (1354201-42-5)

Guidance literature:

With pyridine; hydrogen fluoride; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1021/co2001907

Reference yield:

C28H37N3O2Si → C19H17N3O2 (1354201-42-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1002/cmdc.202100062

Reference yield:

C11H11BrO3 (908567-28-2) → C19H17N3O2 (1354201-42-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium tetrahydroborate; ethanol / 40 °C

1.2: 80 °C

1.3: 20 °C

2.1: trifluorormethanesulfonic acid / dichloromethane / 15 h / 0 - 20 °C

2.2: 2 h / 20 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 60 °C / Inert atmosphere

4.1: bromotris(triphenylphosphine)copper(I); N-ethyl-N,N-diisopropylamine / toluene / 5 h / 40 °C

5.1: pyridine; hydrogen fluoride / tetrahydrofuran / 2 h / 20 °C

With pyridine; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromotris(triphenylphosphine)copper(I); ethanol; trifluorormethanesulfonic acid; hydrogen fluoride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; toluene; 3.1: Stille coupling;

DOI:10.1021/co2001907

upstream raw materials:

C₁₁H₁₁BrO₃

2',4'-dihydroxy-4-acetophenone

7-hydroxy-2,2-dimethyl-chroman-4-one

C₁₁H₁₁BrO₂