(R)-3-Amino-3-(o-tolyl)propanoic acid

Base Information

Chemical Name:(R)-3-Amino-3-(o-tolyl)propanoic acid
CAS No.:752198-38-2
Molecular Formula:C₁₀H₁₃NO₂
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID60375887
Mol file:752198-38-2.mol

Synonyms:752198-38-2;(R)-3-Amino-3-(o-tolyl)propanoic acid;(R)-3-Amino-3-(2-methyl-phenyl)-propionic acid;(3R)-3-amino-3-(2-methylphenyl)propanoic acid;(3R)-3-Amino-3-(o-tolyl)propanoic acid;MFCD04113646;D-3-Amino-3-(2-methylphenyl)-propionic acid;(R)-3-amino-3-(2-methylphenyl)propanoic acid;(R)-3-Amino-3-(2-methylphenyl)propionic acid;(R)-3-Amino-3-(o-tolyl)propanoicacid;SCHEMBL5720952;DTXSID60375887;AKOS010393208;AC-22042;PS-12461;CS-0152985;(R)-3-AMINO-3-O-TOLYLPROPANOIC ACID;EN300-697505

Suppliers and Price of (R)-3-Amino-3-(o-tolyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

JR MediChem
Benzenepropanoicacid,?-amino-2-methyl-,(?R) 96%
5g
$ 1280.00

JR MediChem
Benzenepropanoicacid,?-amino-2-methyl-,(?R) 96%
25g
$ 4980.00

JR MediChem
Benzenepropanoicacid,?-amino-2-methyl-,(?R) 96%
1g
$ 398.00

Crysdot
(R)-3-Amino-3-(o-tolyl)propanoicacid 95+%
5g
$ 545.00

ChemPep
H-D-β-Phe(2-Me)-OH
25g
$ 1590.00

ChemPep
H-D-β-Phe(2-Me)-OH
5g
$ 530.00

Chem-Impex
(R)-3-Amino-3-(2-methylphenyl)propionicacid,≥98% ≥98%
100MG
$ 58.24

Chem-Impex
(R)-3-Amino-3-(2-methylphenyl)propionicacid,≥98% ≥98%
250MG
$ 93.18

Chem-Impex
(R)-3-Amino-3-(2-methylphenyl)propionicacid,≥98% ≥98%
1G
$ 186.37

Chem-Impex
(R)-3-Amino-3-(2-methylphenyl)propionicacid,≥98% ≥98%
5G
$ 669.76

Total 36 raw suppliers

Chemical Property of (R)-3-Amino-3-(o-tolyl)propanoic acid

Chemical Property:

Vapor Pressure:8.82E-05mmHg at 25°C
Refractive Index:1.567
Boiling Point:326.3 °C at 760 mmHg
Flash Point:151.2 °C
PSA：63.32000
Density:1.163 g/cm³
LogP:2.16980
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:-1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:182

Purity/Quality:

97% ^*data from raw suppliers

Benzenepropanoicacid,?-amino-2-methyl-,(?R) 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C(CC(=O)O)N
Isomeric SMILES:CC1=CC=CC=C1[C@@H](CC(=O)O)N

Technology Process of (R)-3-Amino-3-(o-tolyl)propanoic acid

There total 31 articles about (R)-3-Amino-3-(o-tolyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 141-82-2
malonic acid

: 529-20-4
2-methylphenyl aldehyde

: 68208-16-2,752198-38-2
3-amino-3-(2-methylphenyl)propionic acid

Guidance literature:: With ammonium formate; In ethanol; for 4h; Reflux;
DOI:10.1002/adsc.201600894

Reference yield: 48.0%

: 21464-57-3
ethyl 3-amino-3-(o-tolyl)propanoate

: 736131-48-9,752198-38-2
(S)-3-amino-3-(2-methylphenyl)propionic acid

: 1292457-13-6
ethyl (R)-3-amino-3-(o-tolyl)propanoate

Guidance literature:: With water; In tert-butyl methyl ether; at 45 ℃; for 7h; Concentration; Solvent; Temperature; Time; enantioselective reaction; Catalytic behavior; Enzymatic reaction;
DOI:10.1016/j.molcatb.2013.04.001

Reference yield: 47.0%

: 1448452-64-9
1-(hydroxymethyl)-4-(o-tolyl)azetidin-2-one

: 752198-38-2
(R)-3-amino-3-(2-methylphenyl)propionic acid

: 1448452-65-0
(S)-1-(hydroxymethyl)-4-(o-tolyl)azetidin-2-one

Guidance literature:: With water; benzylamine; lipase B from Candida antarctica; In di-isopropyl ether; at 60 ℃; for 24h; enantioselective reaction; Resolution of racemate; Enzymatic reaction;
DOI:10.1002/ejoc.201600234