3-Cyanopiperidine

Base Information

Chemical Name:3-Cyanopiperidine
CAS No.:7492-88-8
Molecular Formula:C6H10N2
Molecular Weight:110.159
Hs Code.:2933399090
European Community (EC) Number:814-245-3
DSSTox Substance ID:DTXSID10329537
Nikkaji Number:J1.756.664D
Mol file:7492-88-8.mol

Synonyms:3-cyanopiperidine;7492-88-8;Piperidine-3-carbonitrile;3-PIPERIDINECARBONITRILE;MFCD01321091;Pperdne-3-carbontrle;3-Piperidinecarbonitrl;SCHEMBL1019673;(RS)-piperidine-3-carbonitrile;DTXSID10329537;(+/-)-piperidine-3-carbonitrile;3-piperidinecarbonitrile, AldrichCPR;BBL101353;STL555149;AKOS005146132;AB09048;AM804318;AS-42157;SY004324;CS-0315616;FT-0688069;EN300-81012;A21964;J-523974

Suppliers and Price of 3-Cyanopiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Cyanopiperidine
1g
$ 360.00

SynQuest Laboratories
Piperidine-3-carbonitrile 98.0%
5 g
$ 706.00

SynQuest Laboratories
Piperidine-3-carbonitrile 98.0%
250 mg
$ 50.00

SynQuest Laboratories
Piperidine-3-carbonitrile 98.0%
1 g
$ 202.00

Matrix Scientific
3-Cyanopiperidine 95%
5g
$ 857.00

Matrix Scientific
3-Cyanopiperidine 95%
1g
$ 286.00

Matrix Scientific
3-Cyanopiperidine 95%
500mg
$ 179.00

Crysdot
Piperidine-3-carbonitrile 95+%
1g
$ 85.00

Crysdot
Piperidine-3-carbonitrile 95+%
5g
$ 283.00

CHESS?
Piperidine-3-carbonitrile >98
5 g
$ 30000.00

Total 30 raw suppliers

Chemical Property of 3-Cyanopiperidine

Chemical Property:

Vapor Pressure:0.082mmHg at 25°C
Refractive Index:1.475
Boiling Point:226.4 °C at 760 mmHg
PKA:8.37±0.10(Predicted)
Flash Point:90.7 °C
PSA：35.82000
Density:0.98 g/cm³
LogP:0.83838
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:110.084398327
Heavy Atom Count:8
Complexity:111

Purity/Quality:

97% ^*data from raw suppliers

3-Cyanopiperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CNC1)C#N
Uses 3-Cyanopiperidine is an intermediate used to prepare pyrazolopyrimidine janus kinase inhibitors useful in the treatment of JAK-associated diseases. It is also used in the synthesis of triazines and related compds. as antiviral agents for treating HCV infection and HCV-assocd. disorders.

Technology Process of 3-Cyanopiperidine

There total 2 articles about 3-Cyanopiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 91419-53-3
(+/-)-2-N-tert-butoxycabonylpiperidine-3-carbonitrile

: 7492-88-8,1159736-73-8
piperidine-3-carbonitrile hydrochloride

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 7492-88-8,1159736-73-8
piperidine-3-carbonitrile hydrochloride

Guidance literature:: Nicotinsaeureamid, Diglyme, 140grad; neben 3-Cyan-1,4,5,6-tetrahydro-pyridin;
DOI:10.1021/jo01278a086

Reference yield: 85.0%

: 1189852-14-9
N-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)-4-(2-hydroxypropan-2-yl)benzamide

: 7492-88-8,1159736-73-8
piperidine-3-carbonitrile hydrochloride

: 76-05-1
trifluoroacetic acid

: (x)C₂HF₃O₂*C₂₂H₂₄N₆O₂

Guidance literature:: N-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)-4-(2-hydroxypropan-2-yl)benzamide; piperidine-3-carbonitrile hydrochloride; In 1-methyl-pyrrolidin-2-one; at 85 ℃;

trifluoroacetic acid; In 1-methyl-pyrrolidin-2-one; methanol; water; dimethyl sulfoxide; acetonitrile; HPLC;