N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide

Base Information

• Chemical Name: N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide
• CAS No.: 218769-25-6
• Molecular Formula: C₄₁H₆₀N₈O₇
• Molecular Weight: 776.977

Synonyms:

Chemical Property of N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide

There total 4 articles about N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 6-<<<(S)-2-<(t-butoxycarbonyl)amino>-2-(carbamoyl)-ethyl>amino>methyl>pyridine-2-carboxylate (80109-36-0) → Nα-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide (218769-25-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 82.4 percent / 0.2M aq. NaOH / CH₂Cl₂ / 3 h / Ambient temperature

2: 0.1M aq. LiOH / tetrahydrofuran / 1.5 h

3: 1.) diphenylphosphoryl azide, 2.) Et₃N / 1.) DMF, 0 deg C, 20 min, 2.) DMF, a) 0 deg C, 3 h, b) RT, 2 d

With lithium hydroxide; sodium hydroxide; diphenylphosphoranyl azide; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1248/cpb.46.1635

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → Nα-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide (218769-25-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 82.4 percent / 0.2M aq. NaOH / CH₂Cl₂ / 3 h / Ambient temperature

2: 0.1M aq. LiOH / tetrahydrofuran / 1.5 h

3: 1.) diphenylphosphoryl azide, 2.) Et₃N / 1.) DMF, 0 deg C, 20 min, 2.) DMF, a) 0 deg C, 3 h, b) RT, 2 d

With lithium hydroxide; sodium hydroxide; diphenylphosphoranyl azide; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1248/cpb.46.1635

Reference yield:

methyl 6-<-2-(carbamoyl)ethyl>amino>methyl>pyridine-2-carboxylate (80109-37-1) → Nα-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide (218769-25-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.1M aq. LiOH / tetrahydrofuran / 1.5 h

2: 1.) diphenylphosphoryl azide, 2.) Et₃N / 1.) DMF, 0 deg C, 20 min, 2.) DMF, a) 0 deg C, 3 h, b) RT, 2 d

With lithium hydroxide; diphenylphosphoranyl azide; triethylamine; In tetrahydrofuran;

DOI:10.1248/cpb.46.1635

upstream raw materials:

(S)-2-Amino-N-dodecyl-3-(1H-imidazol-4-yl)-propionamide

6-{[Benzyloxycarbonyl-((S)-2-tert-butoxycarbonylamino-2-carbamoyl-ethyl)-amino]-methyl}-pyridine-2-carboxylic acid

methyl 6-<<<(S)-2-<(t-butoxycarbonyl)amino>-2-(carbamoyl)-ethyl>amino>methyl>pyridine-2-carboxylate

benzyl chloroformate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 218769-25-6 N^α-<6-<ethyl>-N-(benzoyloxycarbonyl)-amino>methyl>pyridine-2-carbonyl>-L-histidine laurylamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send