1β-Methyl-1-phenylcyclohexane

Base Information

• Chemical Name: 1β-Methyl-1-phenylcyclohexane
• CAS No.: 828-45-5
• Molecular Formula: C13H18
• Molecular Weight: 174.286
• Mol file: 828-45-5.mol

Synonyms:1-Methyl-1-phenylcyclohexane;NSC 54370

Chemical Property of 1β-Methyl-1-phenylcyclohexane

Chemical Property:

• Vapor Pressure: 0.038mmHg at 25°C
• Boiling Point: 248.6°C at 760 mmHg
• Flash Point: 97°C
• PSA: 0.00000
• Density: 0.921g/cm³
• LogP: 3.90840

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1β-Methyl-1-phenylcyclohexane

There total 44 articles about 1β-Methyl-1-phenylcyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trimethylaluminum (75-24-1) + 2,2-dimethyl-5-(1-phenylcyclohexyl)-1,3-dioxane-4,6-dione (83485-31-8) → 1-methylcyclohexylbenzene (828-45-5)

Guidance literature:

In n-heptane; dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1021/ol301442z

Reference yield: 95.0%

7-chloro-2-methylseleno-2-phenyl-heptane → 1-methylcyclohexylbenzene (828-45-5)

Guidance literature:

With tert.-butyl lithium; pentane; In tetrahydrofuran; at -78 ℃; for 0.1h;

DOI:10.1016/S0040-4020(01)85242-X

Reference yield: 86.0%

4-methyl-4-phenylcyclohexan-1-one (18932-33-7) → 1-methylcyclohexylbenzene (828-45-5)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; 1.) reflux, 2 h, 2.) to 195 deg C, 6 h;

DOI:10.1021/jo00322a056

upstream raw materials:

1-methylcyclohex-1-ene

p-methylcyclohexanol

di-tert-butyl peroxide

(1-phenyl-cyclohexyl)-acetaldehyde

Downstream raw materials:

hexabromobenzene

1-methyl-1-(4-nitrophenyl)cyclohexane

benzoic acid

ethylcyclopentane

Refernces

• 1、 Zultanski, Susan L.,Fu, Gregory C.. "Nickel-catalyzed carbon-carbon bond-forming reactions of unactivated tertiary alkyl halides: Suzuki arylations". supporting information. p. 624 - 627. Retrieved 2013/03/14.
• 2、 -. "CATALYST FOR ASYMMETRIC HYDROGENATION". Page/Page column 51-52. . Retrieved 2010/12/31.