methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate

Base Information

• Chemical Name: methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate
• CAS No.: 98777-62-9
• Molecular Formula: C₁₃H₁₆ClNO₅
• Molecular Weight: 301.727
• Mol file: 98777-62-9.mol

Synonyms:

Chemical Property of methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate

There total 5 articles about methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl DL-2-<(benzyloxy)carbonylamino>-3,4-epoxybutanoate (98777-29-8,98777-30-1,117751-78-7,117751-79-8,141043-28-9,141043-29-0) → methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate (98777-62-9,98777-63-0,105015-95-0,142698-78-0,142698-79-1)

Guidance literature:

With hydrogenchloride; In methanol; for 1.5h; Ambient temperature;

Reference yield:

N-(benzyloxycarbonyl)methionine (4434-61-1) → methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate (98777-62-9,98777-63-0,105015-95-0,142698-78-0,142698-79-1)

Guidance literature:

Multi-step reaction with 5 steps

1: diethyl ether

2: NaIO₄ / methanol; H₂O / 2 h / 0 °C

3: xylene / 36 h / Heating

4: m-chloroperbenzoic acid / CH₂Cl₂ / Ambient temperature

5: HCl / methanol / 1.5 h / Ambient temperature

With hydrogenchloride; sodium periodate; 3-chloro-benzenecarboperoxoic acid; In methanol; diethyl ether; dichloromethane; water; xylene;

Reference yield:

N-<(benzyloxy)carbonyl>-DL-methionine methyl ester (83972-33-2) → methyl DL-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate (98777-62-9,98777-63-0,105015-95-0,142698-78-0,142698-79-1)

Guidance literature:

Multi-step reaction with 4 steps

1: NaIO₄ / methanol; H₂O / 2 h / 0 °C

2: xylene / 36 h / Heating

3: m-chloroperbenzoic acid / CH₂Cl₂ / Ambient temperature

4: HCl / methanol / 1.5 h / Ambient temperature

With hydrogenchloride; sodium periodate; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; water; xylene;

upstream raw materials:

methyl DL-2-<(benzyloxy)carbonylamino>-3,4-epoxybutanoate

N-(benzyloxycarbonyl)methionine

N-<(benzyloxy)carbonyl>-DL-methionine methyl ester

N-<(benzoyloxy)carbonyl>-D,L-vinylglycine methyl ester

Refernces