22-hydroxylanosterol

Base Information

Chemical Name:22-hydroxylanosterol
CAS No.:64907-49-9
Molecular Formula:C₃₀H₅₀O₂
Molecular Weight:442.726
Hs Code.:

Synonyms:

Suppliers and Price of 22-hydroxylanosterol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 22-hydroxylanosterol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 22-hydroxylanosterol

There total 18 articles about 22-hydroxylanosterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 114683-10-2,114683-11-3
(22R)-22-Hydroxy-3β-(t-butyldimethylsiloxy)lanosta-8,24-diene

: 35963-37-2,64907-49-9
(22R)-3β,22-Dihydroxylanosta-8,24-diene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 15h; Yield given; Ambient temperature;
DOI:10.1055/s-1987-28048

Reference yield:

: 79-63-0,514-46-5,514-47-6,13879-06-6,19044-12-3,76582-59-7,82570-26-1,84924-98-1,107596-76-9,110269-67-5
Lanosterol

: 35963-37-2,64907-49-9
(22R)-3β,22-Dihydroxylanosta-8,24-diene

Guidance literature:: Multi-step reaction with 10 steps

1: I₂/Cu(OAc)2*H₂O / CH₂Cl₂ / 1 h / Ambient temperature

2: t-C₄H₉OK / tetrahydrofuran / 2.5 h / Heating

3: 90 percent / AcCl, NaI / acetonitrile; CH₂Cl₂ / 0.08 h / Ambient temperature

4: 95 percent / imidazole / dimethylformamide / 15 h / Ambient temperature

5: 100 percent / 90percent m-chloroperbenzoic acid/KF / CH₂Cl₂ / 0.75 h / Ambient temperature

6: 61 percent / O₃, pyridine / CH₂Cl₂ / -78 °C

7: 2.) LiBH(C₂H₅)3 / 1.) THF, -78 deg C to room temp., 3 h, 2.) room temp., 15 h

8: 95 percent / pyridine / 5 h / 0 °C

9: 73 percent / potassium superoxide, 18-crown-6 / dimethylformamide; dimethylsulfoxide / 5 h / Ambient temperature

10: tetrabutylammonium fluoride / tetrahydrofuran / 15 h / Ambient temperature

With pyridine; 1H-imidazole; potassium superoxide; potassium fluoride; copper diacetate; 18-crown-6 ether; potassium tert-butylate; tetrabutyl ammonium fluoride; iodine; lithium triethylborohydride; ozone; acetyl chloride; 3-chloro-benzenecarboperoxoic acid; sodium iodide; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-1987-28048

Reference yield:

: 42895-54-5,114718-54-6
Lanosta-8,22,24-triene-3β-ol

: 35963-37-2,64907-49-9
(22R)-3β,22-Dihydroxylanosta-8,24-diene

Guidance literature:: Multi-step reaction with 7 steps

1: 95 percent / imidazole / dimethylformamide / 15 h / Ambient temperature

2: 100 percent / 90percent m-chloroperbenzoic acid/KF / CH₂Cl₂ / 0.75 h / Ambient temperature

3: 61 percent / O₃, pyridine / CH₂Cl₂ / -78 °C

4: 2.) LiBH(C₂H₅)3 / 1.) THF, -78 deg C to room temp., 3 h, 2.) room temp., 15 h

5: 95 percent / pyridine / 5 h / 0 °C

6: 73 percent / potassium superoxide, 18-crown-6 / dimethylformamide; dimethylsulfoxide / 5 h / Ambient temperature

7: tetrabutylammonium fluoride / tetrahydrofuran / 15 h / Ambient temperature

With pyridine; 1H-imidazole; potassium superoxide; potassium fluoride; 18-crown-6 ether; tetrabutyl ammonium fluoride; lithium triethylborohydride; ozone; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1055/s-1987-28048