2-Chloro-1,6-naphthyridine

Base Information

Chemical Name:2-Chloro-1,6-naphthyridine
CAS No.:23616-33-3
Molecular Formula:C8H5ClN2
Molecular Weight:164.594
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30543132
Wikidata:Q82419968
Mol file:23616-33-3.mol

Synonyms:2-chloro-1,6-naphthyridine;23616-33-3;1,6-Naphthyridine, 2-chloro-;1,6-Naphthyridin-2-yl chloride;MFCD11044731;1,6-Naphthyridine,2-chloro-;chloro-1,6-naphthyridine;2-Chloro-1,6-naphthyridin;2-chloranyl-1,6-naphthyridine;SCHEMBL3064494;DTXSID30543132;ZKYKRMVSSXLKSB-UHFFFAOYSA-N;AMY23485;YAA61633;2-Chloro-1 pound not6-naphthyridine;AKOS006309176;MB09141;CS-11855;SY031685;CS-0099325;EN300-1197927;A816806;J-508596

Suppliers and Price of 2-Chloro-1,6-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-1,6-naphthyridine
50mg
$ 130.00

TRC
2-Chloro-1,6-naphthyridine
10mg
$ 45.00

Labseeker
2-Chloro-1,6-naphthyridine 95
250mg
$ 539.00

Crysdot
2-Chloro-1,6-naphthyridine 95+%
1g
$ 445.00

American Custom Chemicals Corporation
2-CHLORO-1,6-NAPHTHYRIDINE 95.00%
5MG
$ 499.64

Ambeed
2-Chloro-1,6-naphthyridine 95%
250mg
$ 146.00

Alichem
2-Chloro-1,6-naphthyridine
1g
$ 638.40

Alichem
2-Chloro-1,6-naphthyridine
250mg
$ 260.01

Alichem
2-Chloro-1,6-naphthyridine
5g
$ 1916.25

AK Scientific
2-Chloro-1,6-naphthyridine
1g
$ 790.00

Total 28 raw suppliers

Chemical Property of 2-Chloro-1,6-naphthyridine

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Refractive Index:1.663
Boiling Point:298.922 °C at 760 mmHg
PKA:2.89±0.30(Predicted)
Flash Point:162.817 °C
PSA：25.78000
Density:1.35 g/cm³
LogP:2.28320
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:164.0141259
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-1,6-naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC2=C1C=NC=C2)Cl

Technology Process of 2-Chloro-1,6-naphthyridine

There total 4 articles about 2-Chloro-1,6-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.45%

: 23616-29-7
1,6-naphthyridin-2(1H)-one

: 23616-33-3
2-chloro-1,6-naphthyridine

Guidance literature:: In trichlorophosphate;

Reference yield:

: 13534-98-0
3-bromopyridin-4-amine

: 23616-33-3
2-chloro-1,6-naphthyridine

Guidance literature:: Multi-step reaction with 3 steps

1: palladium diacetate; triphenylphosphine; triethylamine / N,N-dimethyl-formamide / 4 h / 100 °C / Inert atmosphere

2: sodium / ethanol / 2 h / 0 °C / Reflux

3: trichlorophosphate / 16 h / Reflux

With palladium diacetate; sodium; triethylamine; triphenylphosphine; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: (E)-ethyl 3-(4-aminopyridin-3-yl)acrylate

: 23616-33-3
2-chloro-1,6-naphthyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium / ethanol / 2 h / 0 °C / Reflux

2: trichlorophosphate / 16 h / Reflux

With sodium; trichlorophosphate; In ethanol;