D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate

Base Information

Chemical Name:D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate
CAS No.:115224-25-4
Molecular Formula:C₆H₁₄O₁₀P₂
Molecular Weight:308.119
Hs Code.:
DSSTox Substance ID:DTXSID301154845
Wikidata:Q76105711
Metabolomics Workbench ID:146980

Synonyms:D-GLUCO-2,5-ANHYDRO-1-DEOXY-1-PHOSPHONOHEXITOL-6-PHOSPHATE;2,5-anhydro-1-deoxy-1-phosphono-6-O-phosphono-D-glucitol;FDQ;DTXSID301154845;DB02393;D-Glucitol, 2,5-anhydro-1-deoxy-1-phosphono-, 6-(dihydrogen phosphate);115224-25-4

Suppliers and Price of D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate

Chemical Property:

XLogP3:-4.9
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:5
Exact Mass:308.00622063
Heavy Atom Count:18
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C(C1C(C(C(O1)CP(=O)(O)O)O)O)OP(=O)(O)O
Isomeric SMILES:C([C@@H]1[C@H]([C@@H]([C@@H](O1)CP(=O)(O)O)O)O)OP(=O)(O)O

Technology Process of D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate

There total 8 articles about D-Gluco-2,5-anhydro-1-deoxy-1-phosphonohexitol-6-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 160549-10-0
2,3,5-tri-O-benzyl-D-arabinofuranose

: 115224-25-4
((2R,3S,4S,5R)-3,4-Dihydroxy-5-phosphonooxymethyl-tetrahydro-furan-2-ylmethyl)-phosphonic acid

Guidance literature:: Multi-step reaction with 8 steps

1: 68 percent

2: 85 percent / NaH / dimethylformamide

3: bromine / CCl₄

4: 85 percent / H₂SO₄,

5: 85 percent / NaOH / H₂O; methanol

6: 73 percent / pyridine

7: 40 percent / 160 °C

With sodium hydroxide; sulfuric acid; bromine; sodium hydride; In pyridine; methanol; tetrachloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)98686-6

Reference yield:

: 102093-92-5,102208-57-1
Acetic acid (2R,3R,4S)-3,4-bis-benzyloxy-5-bromomethyl-tetrahydro-furan-2-ylmethyl ester

: 115224-25-4
((2R,3S,4S,5R)-3,4-Dihydroxy-5-phosphonooxymethyl-tetrahydro-furan-2-ylmethyl)-phosphonic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / NaOH / H₂O; methanol

2: 73 percent / pyridine

3: 40 percent / 160 °C

With sodium hydroxide; In pyridine; methanol; water;
DOI:10.1016/S0040-4039(00)98686-6

Reference yield:

: 93125-78-1,102208-53-7,137820-47-4
(R)-1,3,4-Tris-benzyloxy-hex-5-en-2-ol

: 115224-25-4
((2R,3S,4S,5R)-3,4-Dihydroxy-5-phosphonooxymethyl-tetrahydro-furan-2-ylmethyl)-phosphonic acid

Guidance literature:: Multi-step reaction with 7 steps

1: 85 percent / NaH / dimethylformamide

2: bromine / CCl₄

3: 85 percent / H₂SO₄,

4: 85 percent / NaOH / H₂O; methanol

5: 73 percent / pyridine

6: 40 percent / 160 °C

With sodium hydroxide; sulfuric acid; bromine; sodium hydride; In pyridine; methanol; tetrachloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)98686-6