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6-Bromo-1,8-naphthyridin-2-amine

Base Information
  • Chemical Name:6-Bromo-1,8-naphthyridin-2-amine
  • CAS No.:64874-38-0
  • Molecular Formula:C8H6 Br N3
  • Molecular Weight:224.06
  • Hs Code.:2933990090
  • European Community (EC) Number:860-098-3
  • DSSTox Substance ID:DTXSID90493124
  • Nikkaji Number:J3.520.831C
  • Wikidata:Q72448356
6-Bromo-1,8-naphthyridin-2-amine

Synonyms:6-BROMO-1,8-NAPHTHYRIDIN-2-AMINE;64874-38-0;2-Amino-6-bromo-1,8-naphthyridine;MFCD09909648;6-Bromo-[1,8]naphthyridin-2-ylamine;SCHEMBL4819657;AMY1697;DTXSID90493124;PEDHUXRIIJIMDP-UHFFFAOYSA-N;AKOS015854964;AB54756;CS-W022447;FS-2732;SY066946;FT-0648670;6-Bromo-1,8-naphthyridin-2-amine, AldrichCPR;EN300-393369;J-507976;Z1269200413

Suppliers and Price of 6-Bromo-1,8-naphthyridin-2-amine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 6-Bromo-1,8-naphthyridin-2-amine
  • 500mg
  • $ 285.00
  • SynQuest Laboratories
  • 2-Amino-6-bromo-1,8-naphthyridine
  • 250 mg
  • $ 264.00
  • SynQuest Laboratories
  • 2-Amino-6-bromo-1,8-naphthyridine
  • 1 g
  • $ 618.00
  • Matrix Scientific
  • 2-Amino-6-bromo-1,8-naphthyridine 95+%
  • 1g
  • $ 1357.00
  • Matrix Scientific
  • 2-Amino-6-bromo-1,8-naphthyridine 95+%
  • 250mg
  • $ 629.00
  • Apolloscientific
  • 2-Amino-6-bromo-1,8-naphthyridine
  • 250mg
  • $ 240.00
  • Apolloscientific
  • 2-Amino-6-bromo-1,8-naphthyridine
  • 1g
  • $ 560.00
  • American Custom Chemicals Corporation
  • 2-AMINO-6-BROMO-1,8-NAPHTHYRIDINE 95.00%
  • 1G
  • $ 2069.76
  • American Custom Chemicals Corporation
  • 2-AMINO-6-BROMO-1,8-NAPHTHYRIDINE 95.00%
  • 250MG
  • $ 332.85
  • Ambeed
  • 6-Bromo-1,8-naphthyridin-2-amine 98+%
  • 1g
  • $ 122.00
Total 30 raw suppliers
Chemical Property of 6-Bromo-1,8-naphthyridin-2-amine
Chemical Property:
  • Vapor Pressure:2.77E-05mmHg at 25°C 
  • Melting Point:210-212 °C (sublm) 
  • Boiling Point:357.2oC at 760 mmHg 
  • PKA:4.15±0.30(Predicted) 
  • Flash Point:169.8oC 
  • PSA:51.80000 
  • Density:1.744g/cm3 
  • LogP:2.55570 
  • Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature 
  • XLogP3:1.8
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:0
  • Exact Mass:222.97451
  • Heavy Atom Count:12
  • Complexity:164
Purity/Quality:

97% *data from raw suppliers

6-Bromo-1,8-naphthyridin-2-amine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Statements: 41 
  • Safety Statements: 26-39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC(=NC2=NC=C(C=C21)Br)N
  • Uses 6-Bromo-1,8-naphthyridin-2-amine is used as a reactant in the preparation of substituted naphthyridines as H-PGDS inhibitors.
Technology Process of 6-Bromo-1,8-naphthyridin-2-amine

There total 3 articles about 6-Bromo-1,8-naphthyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With acetic acid; In acetonitrile; for 3h; Reflux;
DOI:10.1002/jhet.2694
Guidance literature:
With phosphoric acid; at 0 - 120 ℃; for 16h; Inert atmosphere;
Guidance literature:
2.6-Diaminopyridin (1), 2-Bromomalonaldehyd (2d), Orthophosphorsaeure;
DOI:10.1016/S0040-4039(01)83687-X
upstream raw materials:

2.6-diaminopyridine

2-Bromo-malonaldehyde

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