Technology Process of C43H55N3O3S
There total 4 articles about C43H55N3O3S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C32H37F3N2O4S;
With
Benzophenone imine; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
toluene;
at 110 ℃;
for 24h;
Inert atmosphere;
2,4,6-triethylbenzene-1-sulfonyl chloride;
With
pyridine; dmap;
In
dichloromethane;
at 30 ℃;
for 15h;
Inert atmosphere;
DOI:10.1021/ol302427d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 20 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 12 h / 20 °C
3.1: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; Benzophenone imine; caesium carbonate / toluene / 24 h / 110 °C / Inert atmosphere
3.2: 15 h / 30 °C / Inert atmosphere
With
Benzophenone imine; palladium diacetate; sodium hydride; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine;
In
dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/ol302427d
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 12 h / 20 °C
2.1: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; Benzophenone imine; caesium carbonate / toluene / 24 h / 110 °C / Inert atmosphere
2.2: 15 h / 30 °C / Inert atmosphere
With
Benzophenone imine; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine;
In
dichloromethane; toluene;
DOI:10.1021/ol302427d
