tert-Butyl 3-(bromomethyl)phenylcarbamate

Base Information

Chemical Name:tert-Butyl 3-(bromomethyl)phenylcarbamate
CAS No.:118684-32-5
Molecular Formula:C12H16 Br N O2
Molecular Weight:286.169
Hs Code.:2924299090
European Community (EC) Number:888-325-1
DSSTox Substance ID:DTXSID501219334
Mol file:118684-32-5.mol

Synonyms:118684-32-5;tert-Butyl 3-(bromomethyl)phenylcarbamate;tert-Butyl (3-(bromomethyl)phenyl)carbamate;N-Boc-3-(bromomethyl)aniline;TERT-BUTYL N-[3-(BROMOMETHYL)PHENYL]CARBAMATE;MFCD11974927;tert-Butyl(3-(bromomethyl)phenyl)carbamate;tert-butyl[3-(bromomethyl)phenyl]carbamate;tert-butyl [3-(bromomethyl)phenyl]carbamate;Carbamic acid, [3-(bromomethyl)phenyl]-, 1,1-dimethylethyl ester;2-Methyl-2-propanyl [3-(bromomethyl)phenyl]carbamate;SCHEMBL1865895;[3-[N-(tert-butoxycarbonyl)amino]phenyl]methyl bromide;AMY4898;HQPYEVSQMSDBFG-UHFFFAOYSA-N;DTXSID501219334;AKOS015909995;CS-W005159;DS-7459;tert-butyl3-(bromomethyl)phenylcarbamate;3-(Bromomethyl)aniline, N-BOC protected;SY104579;3-(Tert-butoxycarbonylamino)benzyl bromide;F12042;EN300-1883049;A893015;(3-bromomethyl-phenyl)-carbamic acid tert-butyl ester;1,1-Dimethylethyl N-[3-(bromomethyl)phenyl]carbamate;Carbamic acid,N-[3-(bromomethyl)phenyl]-,1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl 3-(bromomethyl)phenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(3-(bromomethyl)phenyl)carbamate 95%
10g
$ 465.00

Crysdot
tert-Butyl(3-(bromomethyl)phenyl)carbamate 95%
25g
$ 932.00

Crysdot
tert-Butyl(3-(bromomethyl)phenyl)carbamate 95%
5g
$ 239.00

Apolloscientific
3-(Bromomethyl)aniline, N-BOC protected
1g
$ 98.00

Apolloscientific
3-(Bromomethyl)aniline, N-BOC protected
5g
$ 345.00

Alichem
tert-Butyl(3-(bromomethyl)phenyl)carbamate
10g
$ 480.00

Alichem
tert-Butyl(3-(bromomethyl)phenyl)carbamate
5g
$ 331.24

AK Scientific
tert-Butyl3-(bromomethyl)phenylcarbamate
1g
$ 132.00

Abosyn
tert-Butyl(3-(bromomethyl)phenyl)carbamate 95-98%
5g
$ 432.00

Total 24 raw suppliers

Chemical Property of tert-Butyl 3-(bromomethyl)phenylcarbamate

Chemical Property:

Melting Point:122 °C
Boiling Point:309.0±25.0 °C(Predicted)
PKA:13.58±0.70(Predicted)
PSA：38.33000
Density:1.376±0.06 g/cm3(Predicted)
LogP:4.00150
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:285.03644
Heavy Atom Count:16
Complexity:238

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(3-(bromomethyl)phenyl)carbamate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=CC(=C1)CBr

Technology Process of tert-Butyl 3-(bromomethyl)phenylcarbamate

There total 5 articles about tert-Butyl 3-(bromomethyl)phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 118684-31-4
tert-butyl N-[3-(hydroxymethyl)phenyl]carbamate

: 118684-32-5
[3-[N-(tert-butoxycarbonyl)amino]phenyl]methyl bromide

Guidance literature:: With N-Bromosuccinimide; triphenylphosphine; at -20 ℃; for 3h;

Reference yield:

: 1877-77-6
3-aminobenzenemethanol

: 118684-32-5
[3-[N-(tert-butoxycarbonyl)amino]phenyl]methyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 4 h / Heating

2: CBr₄; PPh₃ / CH₂Cl₂ / 1 h / 0 °C

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; dichloromethane; 1: Substitution / 2: Substitution;
DOI:10.1016/S0040-4020(00)00179-4

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 118684-32-5
[3-[N-(tert-butoxycarbonyl)amino]phenyl]methyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / tetrahydrofuran / 5 h / Heating

2: 74 percent / CBr₄, Ph₃P / CH₂Cl₂ / 1.5 h / 0 °C

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; dichloromethane;