1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one

Base Information

Chemical Name:1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one
CAS No.:447406-53-3
Molecular Formula:C13H10 F3 N O S
Molecular Weight:285.29
Hs Code.:
DSSTox Substance ID:DTXSID00431512
Wikidata:Q72492057
Mol file:447406-53-3.mol

Synonyms:447406-53-3;1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one;1-[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethanone;1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-1-ethanone;1-[4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl]ethanone;SCHEMBL4462657;DTXSID00431512;AKOS008142830;A7101;CS-0274725;FT-0687671;8R-0817;Z735555578;1-(4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)ethan-1-one;1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethanone

Suppliers and Price of 1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-1-ethanone
5g
$ 7343.00

Matrix Scientific
1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-1-ethanone
1g
$ 1836.00

Matrix Scientific
1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-1-ethanone
500mg
$ 918.00

Total 10 raw suppliers

Chemical Property of 1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:365.461oC at 760 mmHg
PKA:0.16±0.10(Predicted)
Flash Point:174.825oC
PSA：58.20000
Density:1.304g/cm3
LogP:4.33990
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:285.04351960
Heavy Atom Count:19
Complexity:339

Purity/Quality:

97% ^*data from raw suppliers

1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-1-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SC(=N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)C

Technology Process of 1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one

There total 1 articles about 1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 72505-21-6
4-trifluoromethylbenzthioamide

: 1694-29-7
3-chloropentane-2,4-dione

: 447406-53-3
1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethanone

Guidance literature:: In ethanol; at 55 - 60 ℃;

Reference yield: 99.0%

: 447406-53-3
1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethanone

: 438577-62-9
[rac]-1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethanol

Guidance literature:: 1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethanone; With sodium tetrahydroborate; In ethanol; at 0 - 20 ℃; for 0.5h;

With water; In ethyl acetate;