(1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

Base Information

Chemical Name:(1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol
CAS No.:143819-31-2
Molecular Formula:C₉H₁₆O
Molecular Weight:140.225
Hs Code.:

Synonyms:

Suppliers and Price of (1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

There total 8 articles about (1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143819-30-1
(R)-2-Methyl-5-ethyl-5-hexenal

: 143819-31-2
(1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

: 143819-16-3
(1S,2R,E)-2-Methyl-5-ethylidenecyclohexanol

Guidance literature:: With dimethylaluminum chloride; In hexane; dichloromethane; at -78 ℃; for 0.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo00048a016

Reference yield:

: 143819-29-8
(R)-2-Methyl-5-ethyl-5-hexen-1-ol

: 143819-31-2
(1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) oxalyl chloride, DMSO, 2.) triethylamine / 1.) CH₂Cl₂, -78 deg C, 30 min, 2.) -78 to 0 deg C

2: Me₂AlCl / CH₂Cl₂; hexane / 0.5 h / -78 °C

With oxalyl dichloride; dimethylaluminum chloride; dimethyl sulfoxide; triethylamine; In hexane; dichloromethane;
DOI:10.1021/jo00048a016

Reference yield:

: 143819-26-5,143900-15-6
(2S,5R)-5-Methyl-2-ethyl-6-<(tetrahydropyranyl)oxy>-1,2-hexanediol

: 143819-31-2
(1S,2R,Z)-2-Methyl-5-ethylidenecyclohexanol

Guidance literature:: Multi-step reaction with 5 steps

1: toluene / 30 h / Heating

2: 77 percent / trimethyl phosphite / 72 h / Heating

3: 91 percent / methanol, PPTS / 48 h / Ambient temperature

4: 1.) oxalyl chloride, DMSO, 2.) triethylamine / 1.) CH₂Cl₂, -78 deg C, 30 min, 2.) -78 to 0 deg C

5: Me₂AlCl / CH₂Cl₂; hexane / 0.5 h / -78 °C

With methanol; oxalyl dichloride; dimethylaluminum chloride; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; phosphorous acid trimethyl ester; In hexane; dichloromethane; toluene;
DOI:10.1021/jo00048a016