(S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate

Base Information

Chemical Name:(S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate
CAS No.:172477-91-7
Molecular Formula:C11H22 N2 O2
Molecular Weight:250.76600
Hs Code.:
European Community (EC) Number:889-287-9
DSSTox Substance ID:DTXSID30692891
Wikidata:Q72497293
Mol file:172477-91-7.mol

Synonyms:172477-91-7;(S)-TERT-BUTYL METHYL(PYRROLIDIN-2-YLMETHYL)CARBAMATE;tert-butyl N-methyl-N-[[(2S)-pyrrolidin-2-yl]methyl]carbamate;(S)-METHYL-(2-PYRROLIDINYLMETHYL)-CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER;tert-butyl N-methyl-N-{[(2S)-pyrrolidin-2-yl]methyl}carbamate;SCHEMBL14473849;DTXSID30692891;A26515;D87948;EN300-7008942;tert-Butyl methyl{[(2S)-pyrrolidin-2-yl]methyl}carbamate;methyl-(S)-1-pyrrolidin-2-ylmethyl-carbamic acid tert-butyl ester;TERT-BUTYL N-METHYL-N-{[(2S)-PYRROLIDIN-2-YL]METHYLCARBAMATE

Suppliers and Price of (S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate

Chemical Property:

Boiling Point:287℃
Flash Point:127℃
PSA：41.57000
Density:0.993
LogP:2.73610
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:214.168127949
Heavy Atom Count:15
Complexity:223

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(C)CC1CCCN1
Isomeric SMILES:CC(C)(C)OC(=O)N(C)C[C@@H]1CCCN1

Technology Process of (S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate

There total 6 articles about (S)-Tert-butyl methyl(pyrrolidin-2-ylmethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 172477-90-6
(S)-1-benzyl-2-<(t-butyloxycarbonyl)methylaminomethyl>-pyrrolidine

: 172477-91-7,1334335-95-3
(S)-2-<(t-butyloxycarbonyl)methylaminomethyl>-pyrrolidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Ambient temperature;
DOI:10.1016/0040-4020(95)00716-L

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 172477-91-7,1334335-95-3
(S)-2-<(t-butyloxycarbonyl)methylaminomethyl>-pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / CHCl₃ / Heating

2: 55 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; chloroform;
DOI:10.1016/0040-4020(95)00716-L

Reference yield:

: 955-40-8,172478-10-3
N-benzyl-L-proline ethyl ester

: 172477-91-7,1334335-95-3
(S)-2-<(t-butyloxycarbonyl)methylaminomethyl>-pyrrolidine

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / H₂O / 100 °C

2: 62 percent / Red-Al / toluene / 2 h / 50 °C

3: 98 percent / CHCl₃ / Heating

4: 55 percent / H₂ / 10percent Pd/C / ethanol / Ambient temperature

With hydrogen; sodium bis(2-methoxyethoxy)aluminium dihydride; palladium on activated charcoal; In ethanol; chloroform; water; toluene;
DOI:10.1016/0040-4020(95)00716-L