3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE

Base Information

• Chemical Name: 3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE
• CAS No.: 169750-76-9
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.335
• Hs Code.: 2933399090
• Mol file: 169750-76-9.mol

Synonyms:3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE;tert-butyl N-methyl-N-(piperidin-3-ylmethyl)carbamate;

Chemical Property of 3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Boiling Point: 306.014oC at 760 mmHg
• PKA: 10.18±0.10(Predicted)
• Flash Point: 138.873oC
• PSA: 41.57000
• Density: 0.978g/cm3
• LogP: 2.18170
• Storage Temp.: 2-8°C

Purity/Quality:

99.5% ^*data from raw suppliers

tert-ButylMethyl(3-piperidinylmethyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE

There total 3 articles about 3-N-BOC-3-N-METHYL-AMINOMETHYL PIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C19H30N2O2 (1124199-20-7) → tert-butyl N-methyl-N-[[(3R)-piperidin-3-yl]methyl]carbamate (1124199-21-8,169750-76-9)

Guidance literature:

With hydrogen; palladium hydroxide on carbon; In ethanol; for 8h; under 3102.97 - 3620.13 Torr;

Reference yield: 51.0%

→ tert-butyl N-methyl-N-[[(3S)-piperidin-3-yl]methyl]carbamate (1124199-22-9,169750-76-9)

Guidance literature:

Reference yield:

→ tert-butyl N-methyl-N-[[(3R)-piperidin-3-yl]methyl]carbamate (1124199-21-8,169750-76-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 15h; Inert atmosphere;

upstream raw materials:

C₁₉H₃₀N₂O₂

Refernces

• 1、 -. "QUINAZOLINEDIONE DERIVATIVE". Paragraph 1628; 1631; 1640; 1641. . Retrieved 2015/03/16.