(R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14

Base Information

• Chemical Name: (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14
• CAS No.: 110230-24-5
• Molecular Formula: C₃₃H₃₇N₃O₁₀S₂
• Molecular Weight: 699.803
• Mol file: 110230-24-5.mol

Synonyms:

Chemical Property of (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14

There total 2 articles about (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

{(R)-1-Fluorocarbonyl-2-[(R)-2-fluorocarbonyl-2-(4-nitro-benzyloxycarbonylamino)-ethyldisulfanyl]-ethyl}-carbamic acid 4-nitro-benzyl ester (95107-93-0) + C47H45NO4Sn2 → (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14 (110230-24-5)

Guidance literature:

In chloroform; benzene; for 1h; Heating;

DOI:10.1016/S0040-4020(01)87317-8

Reference yield:

N,N'-di-p-nitrocarbobenzoxy-L-cystine (95107-90-7) → (R)(R)-(+) N,N' dicarbobenzoxydiamino-8,13 tetraoxa-3,6,15,18 dithia-10,11 aza-24 bicyclo<18.3.1> tetracosatriene-1(24),20,22 dione-7,14 (110230-24-5)

Guidance literature:

Multi-step reaction with 2 steps

1: tosylate de fluoro-2 N-methyl pyridinium, triethylamine / CH₂Cl₂; ethyl acetate / 0.5 h / Ambient temperature

2: 42 percent / benzene; CHCl₃ / 1 h / Heating

With 1-methyl-2-fluoropyridinium p-toluenesulfonate; triethylamine; In dichloromethane; chloroform; ethyl acetate; benzene;

DOI:10.1016/S0040-4020(01)87317-8

upstream raw materials:

{(R)-1-Fluorocarbonyl-2-[(R)-2-fluorocarbonyl-2-(4-nitro-benzyloxycarbonylamino)-ethyldisulfanyl]-ethyl}-carbamic acid 4-nitro-benzyl ester

N,N'-di-p-nitrocarbobenzoxy-L-cystine